Automated Assays

With MassSTAR, we offer a robotic walkaway solution with CE-IVD validated workflows, full traceability and a graphical user interface for simple instrument handling. Various assays for both, clinical LC-MS/MS and HPLC are also available for automation on specific liquid handlers.

Assays with automated sample preparation

Therapeutic Drug Monitoring

Order No.	Assay	Method	Automation platform
93900/1200/DWP	Immunosuppressants ONEMINUTE in Whole Blood	LC-MS/MS	Chromsystems MassSTAR
92713/XT	Antidepressants 1/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92715/XT	Antidepressants 2/Psychostimulants/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92721/XT	Antiepileptic Drugs All-in-One Method in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92716	Antimycotic Drugs/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92722/XT	Mycophenolic Acid in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92712/XT	Neuroleptics 1/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92714/XT2	Neuroleptics 2/EXTENDED 2 in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
23000/F	Antiepileptic Drugs in Serum/Plasma (Fast Elution)	HPLC	Gilson® ASPEC®
23000/HR, A5, A9	Antiepileptic Drugs in Serum/Plasma (High Resolution)	HPLC	Gilson® ASPEC®
49000/A1, A5, A9	Benzodiazepines and Tricyclic Antidepressants in Serum/Plasma	HPLC	Gilson® ASPEC®

More information on the Chromsystems MassSTAR

Vitamin Profiling

Order No.	Assay	Method	Automation platform
62000/1000/F	MassChrom 25-OH-Vitamin D3/D2 in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
34700/F	Vitamins A/E in Serum/Plasma	HPLC	Hamilton + Tecan
34900/F	Vitamins A/E in Serum/Plasma	UHPLC	Hamilton + Tecan
52752/F	Vitamins B1/B6 in Whole Blood	HPLC	Hamilton + Tecan
52952/UHPLC/F	Vitamins B1/B6 in Whole Blood	UHPLC	Hamilton + Tecan

Biogenic Amines

Order No.	Assay	Method	Automation platform
1000/B/A1, A5, A9	VMA, HVA, 5-HIAA in Urine	HPLC	Hamilton + Tecan
2020/A1, A5, A9	Metanephrines in Urine	HPLC	Hamilton + Tecan
6000/A1, A5, A9	Catecholamines in Urine	HPLC	Hamilton + Tecan

Other

Order No.	Assay	Method	Automation platform
47000/A1, A5, A9	t,t-Muconic Acid in Urine	HPLC	Hamilton + Tecan
48000/A1, A5, A9	Crosslinks in Urine	HPLC	Hamilton + Tecan
53000/A1	1-Hydroxypyrene in Urine	HPLC	Hamilton + Tecan
54730/F	CDT in Serum	HPLC	Tecan

Assays with automated sample preparation

The following Chromsystems Assays for Therapeutic Drug Monitoring are available for automated sample preparation:

Order No.	Assay	Method	Automation platform
93900/1200/DWP	Immunosuppressants ONEMINUTE in Whole Blood	LC-MS/MS	Chromsystems MassSTAR
92713/XT	Antidepressants 1/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92715/XT	Antidepressants 2/Psychostimulants/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92721/XT	Antiepileptic Drugs All-in-One Method in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92716	Antimycotic Drugs/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92722/XT	Mycophenolic Acid in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92712/XT	Neuroleptics 1/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
92714/XT2	Neuroleptics 2/EXTENDED 2 in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
23000/F 23000/HR	Antiepileptic Drugs in Serum/Plasma	HPLC	Gilson Flexus®/ASPEC®
49000/A1, A5, A9	Benzodiazepines and Tricyclic Antidepressants in Serum/Plasma	HPLC	Gilson Flexus®/ASPEC®

More information on the Chromsystems MassSTAR

The following Chromsystems Assays for Vitamin Profiling are available for automated sample preparation:

Order No.	Assay	Method	Automation platform
62000/1000/F	MassChrom 25-OH-Vitamin D3/D2 in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR
34700/F	Vitamins A/E in Serum/Plasma	HPLC	Hamilton + Tecan
34900/F	Vitamins A/E in Serum/Plasma	UHPLC	Hamilton + Tecan
52752/F	Vitamins B1/B6 in Whole Blood	HPLC	Hamilton + Tecan
52952/UHPLC/F	Vitamins B1/B6 in Whole Blood	UHPLC	Hamilton + Tecan

More information on the Chromsystems MassSTAR

The following Chromsystems Assays for Biogenic Amines are available for automated sample preparation:

Order No.	Assay	Method	Automation platform
1000/B/A1, A5, A9	VMA, HVA, 5-HIAA in Urine	HPLC	Hamilton + Tecan
2020/A1, A5, A9	Metanephrines in Urine	HPLC	Hamilton + Tecan
6000/A1, A5, A9	Catecholamines in Urine	HPLC	Hamilton + Tecan

The following Chromsystems Assays are also available for automated sample preparation:

Order No.	Assay	Method	Automation platform
47000/A1, A5, A9	t,t-Muconic Acid in Urine	HPLC	Hamilton + Tecan
48000/A1, A5, A9	Crosslinks in Urine	HPLC	Hamilton + Tecan
53000/A1	1-Hydroxypyrene in Urine	HPLC	Hamilton + Tecan
54730/F	CDT in Serum	HPLC	Tecan

Assays with automated sample preparation

The following Chromsystems Assays for Therapeutic Drug Monitoring are available for automated sample preparation:

Order No.	Assay	Method	Automation platform
93900/1200/DWP	Immunosuppressants ONEMINUTE in Whole Blood	LC-MS/MS	Chromsystems MassSTAR **
92713/XT *	Antidepressants 1/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR **
92715/XT *	Antidepressants 2/Psychostimulants/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR **
92721/XT *	Antiepileptic Drugs All-in-One Method in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR **
92722/XT *	Mycophenolic Acid in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR **
92716 *	Antimycotic Drugs/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR **
92712/XT *	Neuroleptics 1/EXTENDED in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR **
92714/XT2 *	Neuroleptics 2/EXTENDED 2 in Serum/Plasma	LC-MS/MS	Chromsystems MassSTAR **
92916 + 92111/1000/F	Mycophenolic Acid in Serum/Plasma	LC-MS/MS	Hamilton + Tecan
92921 + 92111/1000/F	Antiepileptic Drugs in Serum/Plasma	LC-MS/MS	Hamilton + Tecan
23000/F 23000/HR	Antiepileptic Drugs in Serum/Plasma	HPLC	Gilson Flexus®/ASPEC®
49000/A1, A5, A9	Benzodiazepines and Tricyclic Antidepressants in Serum/Plasma	HPLC	Gilson Flexus®/ASPEC®

* When measuring the parameters of this parameter set you also need the:
• MassTox® TDM Basic Kit A for automated sample preparation on Chromsystems MassSTAR (92711)
• Analytical Column MassTox® TDM MasterColumn® A (92110)

** More details on the Chromsystems MassSTAR can be found here.

The following Chromsystems Assays for Therapeutic Drug Monitoring are available for automated sample preparation:

Order No.	Assay	Matrix	Method	Automation platform
93900/1200/DWP	Immunosuppressants ONEMINUTE	Whole Blood	LC-MS/MS	Chromsystems MassSTAR
92713/XT *	Antidepressants 1/EXTENDED	Serum/Plasma
92715/XT *	Antidepressants 2/Psychostimulants/EXTENDED
92721/XT *	Antiepileptic Drugs All-in-One Method
92722/XT *	Mycophenolic Acid
92716 *	Antimycotic Drugs/EXTENDED
92712/XT *	Neuroleptics 1/EXTENDED
92714/XT2 *	Neuroleptics 2/EXTENDED 2
92916 + 92111/1000/F	Mycophenolic Acid	Serum/Plasma	LC-MS/MS	Hamilton + Tecan
92921 + 92111/1000/F	Antiepileptic Drugs	Serum/Plasma	LC-MS/MS	Hamilton + Tecan
23000/F 23000/HR	Antiepileptic Drugs	Serum/Plasma	HPLC	Gilson Flexus®/ASPEC®
49000/A1, A5, A9	Benzodiazepines and Tricyclic Antidepressants	Serum/Plasma	HPLC	Gilson Flexus®/ASPEC®