Coenzyme Q10


Title Summary Year
Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation Simvastatin therapy has beneficial effects on inflammatory markers in plasma, but CoQ10 supplementation seems to have no additional potentiating effect in patients in primary prevention. In contrast, glucose homeostasis may improve with CoQ10 supplementation. Q10 measured with Chromsystems assay. 2019
Recessive Dystonia-Ataxia Syndrome in a Turkish Family Caused by a COX20 (FAM36A) Mutation The authors extend the phenotypic spectrum of a recently identified mutation in COX20 to a recessively inherited, early-onset dystonia-ataxia syndrome that is characterized by reduced complex IV activity. Further, they confirm a pathogenic role of this mutation in cerebellar ataxia, but this mutation seems to be a rather rare cause. Q10 measured with Chromsystems assay. 2014
The Relationships Between Clinical Outcome and the Levels of Total Antioxidant Capacity (TAC) and Coenzyme Q (CoQ 10) in Children With Pandemic Influenza (H 1 N1) and Seasonal Flu Pandemic influenza infection had increased oxidative stress compared to the seasonal influenza. Q10 was measured with Chromsystems assay.  2012
Lower plasma Coenzyme Q10 in depression:
a marker for treatment resistance and chronic
fatigue in depression and a risk factor to
cardiovascular disorder in that illness
The findings that lower CoQ10 is a risk factor to coronary artery disease and
chronic heart failure (CHF) and mortality due to CHF suggest that low CoQ10 is
another factor explaining the risk to cardiovascular disorder in depression. Q10 was measured by Chromsystems assay.
The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene We suggest to give patients both CoQ10 and riboflavin supplementation, especially for long-term treatment of Q10 deficiency. Q10 measured with Chromsystems assay. 2007

Please find here publications as guides for reference ranges or therapeutic ranges. As they may differ from other published data. Data vary depending on patient population and measurement method, please determine ranges for your laboratory. When determining ranges make sure that you comply with local national requirements. 

Title Summary Year
Biochemical Functions of Coenzyme Q10 Review paper on the biochemical functions of coenzyme Q10 2001
Coenzyme Q10 in Health and Disease Review paper on coenzyme Q10, including supplementation and clinical effects.  1990