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Basic Kit A for 1000 Tests - LC-MS/MS

Order No.: 92111/1000, for 1000 tests
Parameters:
200 grouped in 13 sets

Part of the MassTox® TDM Series A
Unique modular system for therapeutic drug monitoring
Provides all components required for complete sample prep and all mobile phases

CE-IVD validated product ready for IVDR within timeframes and transition periods specified by the IVDR-2022 regulation

main product photo

Basic Kit for all Parameters of TDM Series A

Antiarrhythmic Drugs (92923)

Acebutolol, Ajmaline, Amiodarone, Desethylamiodarone, Aprindine, Atenolol, Bisoprolol, Diltiazem, Disopyramide, Dronedarone, Debutyldronedarone, Flecainide, Flunarizine, Gallopamil, Lidocaine, Metoprolol, Mexiletine, Propafenone, Propranolol, Quinidine, Hydroquinidine, Sotalol, Tocainide, Verapamil, Norverapamil

Antidepressants 1/EXTENDED (92913/XT)

Citalopram, N-Desmethylcitalopram, Duloxetine, Fluoxetine, Desmethylfluoxetine, Fluvoxamine, Mirtazapine, N-Desmethylmirtazapine, Paroxetine, Sertraline, N-Desmethylsertraline, Venlafaxine, O-Desmethylvenlafaxine

Antidepressants 2/ Psychostimulants/EXTENDED (92915/XT)

Atomoxetine, Bupropion, Erythro-Dihydrobupropion, Threo-Dihydrobupropion, Hydroxybupropion, Clomethiazole, Dosulepin, N-Desmethyldosulepin, Methylphenidate, Mianserin, Milnacipran, Moclobemide, Opipramol, Reboxetine, Ritalinic acid, Tianeptine, Tranylcypromine, Trazodone, Vilazodone, Vortioxetine

Antiepileptic Drugs All-in-One Method (92921/XT)

Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, 10-OH-Carbamazepine, 10,11-Dihydroxycarbamazepine, Desmethylmesuximide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam, Oxcarbazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Phenytoin, Pregabalin, Primidone, Retigabine, Rufinamide, Stiripentol, Sultiame, Tiagabine, Theophylline, Topiramate, Valproic acid, Vigabatrin, Zonisamide

Anti-HIV Drugs (92924)

Amprenavir, Atazanavir, Darunavir, Delavirdine, Efavirenz, Elvitegravir, Etravirine, Indinavir, Lopinavir, Maraviroc, Nelfinavir, Nelfinavir-M8, Nevirapine, Raltegravir, Rilpivirine, Ritonavir, Saquinavir

Antimycotic Drugs/EXTENDED (92922/XT)

Amphotericin B*, Anidulafungin, Caspofungin, Fluconazole, 5-Flucytosine, Isavuconazole, Itraconazole, Hydroxyitraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole

Benzodiazepines 1 (92917)

Chlordiazepoxide, Clobazam, Norclobazam, Demoxepam, Diazepam, Nordiazepam, Medazepam, Midazolam, 1-OH-Midazolam, Oxazepam, Prazepam, Temazepam, Tetrazepam

Benzodiazepines 2 (92918)

Alprazolam, Bromazepam, Clonazepam, Flunitrazepam, Flurazepam, Desalkylflurazepam, Lorazepam, Lormetazepam, Nitrazepam, Triazolam

Mycophenolic Acid (92916)

Mycophenolic acid, Mycophenolic acid glucuronide

Neuroleptics 1/EXTENDED (92912/XT)

Aripiprazole, Dehydroaripiprazole, Clozapine, N-Desmethylclozapine, Haloperidol, Olanzapine, N-Desmethylolanzapine, Quetiapine, Norquetiapine, Risperidone, 9-OH-Risperidone

Neuroleptics 2/EXTENDED 2 (92914/XT2)

Amisulpride, Benperidol, Brexpiprazole, Bromperidol, Cariprazine, Chlorpromazine, Chlorprothixene, Flupentixol, Fluphenazine, Guanfacine, Iloperidone, Levomepromazine, Loxapine, Lurasidone, Melperone, Perazine, Perphenazine, Pimozide, Pipamperone, Promethazine, Prothipendyl, Sertindole, Sulforidazine, Sulpiride, Thioridazine, Ziprasidone, Zotepine, Zuclopenthixol

Tricyclic Antidepressants TCA1 (92919)

Amitriptyline, Desipramine, Doxepin, Nordoxepin, Imipramine, Nortriptyline

Tricyclic Antidepressants TCA2 (92920)

Clomipramine, Norclomipramine, Maprotiline, Normaprotiline, Protriptyline, Trimipramine, Nortrimipramine

* For Amphotericin B only qualitative information can be obtained, but data are not CE-IVD compliant.

The Basic Kit A is a part of the Series A modular system, which enables the analysis of nearly 200 parameters without switching column or changing the mobile phases, thereby minimising the required workload in the laboratory. The Basic Kit A contains all components required for sample preparation and all necessary mobile phases.

The Basic Kit A is available for 200 and 1000 analyses.

We also offer an automated version 92111/1000/F.

Further component of the modular system is the MasterColumn® A, an analytical column used for the determination of all Series A analytes. Different Parameter Sets can be selected depending on the drug category – the portfolio covers 14 Parameter Sets for the determination of nearly 200 substances and metabolites.

 

Content

  • 3 x Mobile Phase 1 (92001)
  • 3 x Mobile Phase 2 (92002)
  • 5 x Precipitation Reagent (92003)
  • 5 x Extraction Buffer (92005)
  • 5 x Dilution Buffer 1 (92007)
  • 5 x Dilution Buffer 2 (92008)
  • 2 x Rinsing Solution (92009)
  • 10 x Reaction vials (33006)
More Information
Method of Analysis LC-MS/MS
Number of Tests 1000
Sample Preparation

The sample preparation is standard for all Series A parameters.

  • Add 800 µl Internal Standard Mix to 12 ml Precipitation Reagent to form mixture A.
  • Place 50 µl sample/calibrator/MassCheck® control into a 1.5 ml reaction vial.
  • Add 25 µl Extraction Buffer.
  • Mix and incubate 2 min at ambient temperature (do not centrifuge).
  • Add 250 µl of mixture A and mix 30 s minimum (vortex).
  • Centrifuge 5 min at 15000 x g
  • Dilute the supernatant with Dilution Buffer prior to injection depending on instrument sensitivity

Samples can be prepared with full or partial automation on a liquid handling device, too.
Please note The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals.
Parameter 200 grouped in 13 sets
  1. 92001 LCMS TDM Series A mobile phase1
    Mobile Phase 1
    Order no.: 92001

    MassTox® TDM Series A

    Details
  2. 92002 LCMS MassTox TDM Series A Mobile Phase 2
    Mobile Phase 2
    Order no.: 92002

    MassTox® TDM Series A

    Details
  3. 92003 LCMS TDM Series A precipitation reagent
    Precipitation Reagent
    Order no.: 92003

    MassTox® TDM Series A

    Details
  4. 92005 LCMS TDM Series A extraction buffer
    Extraction Buffer
    Order no.: 92005

    MassTox® TDM Series A

    Details
  5. 92007 LCMS TDM Series A dilution buffer1
    Dilution Buffer 1
    Order no.: 92007

    MassTox® TDM Series A

    Details
  6. 92008 LCMS TDM Series A dilution buffer2
    Dilution Buffer 2
    Order no.: 92008

    MassTox® TDM Series A

    Details
  7. 92009 LCMS TDM Series A rinsing solution
    Rinsing Solution
    Order no.: 92009

    MassTox® TDM Series A

    Details
  8. Reaction Vials, transparent, 1.5 ml
    Reaction Vials, transparent, 1.5 ml
    Order no.: 33006
    Transparent
    Details
  1. 92110 TDM Series A Master Column
    MassTox® TDM MasterColumn® A
    Order no.: 92110

    Analytical column for MassTox® TDM Series A - LC-MS/MS

    Details
  1. 92110 TDM Series A Master Column
    MassTox® TDM MasterColumn® A
    Order no.: 92110

    Analytical column for MassTox® TDM Series A - LC-MS/MS

    Details
  2. PEEK-encased Prefilter, 2 µm
    PEEK-encased Prefilter, 2 µm
    Order no.: 15011
    Details
  3. PEEK Prefilter Housing
    PEEK Prefilter Housing
    Order no.: 15010
    Details
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