MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
Simple and non-invasive sample collection
Easy sample preparation
Complete solution from sample to result
Reliable, robust and proven CE-IVD method
CE-IVD validated product ready for IVDR within timeframes and transition periods specified by the IVDR 2017/746
Cortisol
Cortisone
Clinical relevance
Cortisol and cortisone are steroid hormones that play a role in a range of diseases - one of the most common uses in clinical laboratories is the screening of Cushing’s syndrome and Addison’s disease. However, symptoms are not specific, requiring the precise and efficient determination of these parameters in the clinical laboratory.
Product advantages
- Simple and non-invasive sample collection
Saliva is a matrix that can be obtained very easily and for patients in a non-invasive manner. Stress-induced adrenal stress responses are thereby eliminated, making salivary sampling more reliable. This is of particular importance in stress research and pediatric applications. - Easy sample preparation
The efficient sample preparation takes place in just a few steps. - Complete solution from sample to result
This assay offers everything required for the determination, eliminating the need to develop your own laboratory tests. We also provide you with an excellent on-site support for installation, testing and more. - Reliable, robust and proven CE-IVD method
With our CE-IVD method you gain access to LC-MS/MS as the best available assay for an accurate steroid analysis. The parameters are determined directly without the risk of cross-reactivity as described for immunoassays. You can trust your test results with specific co-eluting internal standards, human-matrix based multilevel calibrators and MassCheck® controls.
Method of Analysis | LC-MS/MS |
---|---|
Number of Tests | 400 |
Please note | The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals. |
Lower Limit of Quantitation | 0.3 µg/l |
Upper Limit of Quantification | up to 120 μg/l (Cortisol) |
Intraassay | CV = 2–5 % |
Interassay | CV = 2–9 % |
Recovery | 96–105 % |
Specimen | Saliva |
Sample Preparation |
|
Run Time | 4.6 min |
Injection Volume | ≤ 30 µl |
Column Temperature | ambient (~ 25 °C) |
Gradient | binary |
Ionisation | ESI positive |
MS/MS Mode | MRM |
Parameters | Cortisol, Cortisone |
-
Analytical Column Cortisol, Cortisone in Saliva - LC-MS/MSOrder no.: 73100
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
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6PLUS1® Multilevel Saliva Calibrator Set Cortisol, CortisoneOrder no.: 73040MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
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MassCheck® Cortisol, Cortisone Saliva Controls (lyoph.)Order no.: 0353/0354
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
System Check Solution MassChrom® Steroid Panel 1Order no.: 72088
MassChrom® Steroids in Serum/Plasma - LC-MS/MS
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
6PLUS1® Multilevel Saliva Calibrator Set Cortisol, CortisoneOrder no.: 73040MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
MassCheck® Cortisol, Cortisone Saliva Controls (lyoph.)Order no.: 0353/0354
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
Analytical Column Cortisol, Cortisone in Saliva - LC-MS/MSOrder no.: 73100
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
Cortisol
Cortisone
Clinical relevance
Cortisol and cortisone are steroid hormones that play a role in a range of diseases - one of the most common uses in clinical laboratories is the screening of Cushing’s syndrome and Addison’s disease. However, symptoms are not specific, requiring the precise and efficient determination of these parameters in the clinical laboratory.
Product advantages
- Simple and non-invasive sample collection
Saliva is a matrix that can be obtained very easily and for patients in a non-invasive manner. Stress-induced adrenal stress responses are thereby eliminated, making salivary sampling more reliable. This is of particular importance in stress research and pediatric applications. - Easy sample preparation
The efficient sample preparation takes place in just a few steps. - Complete solution from sample to result
This assay offers everything required for the determination, eliminating the need to develop your own laboratory tests. We also provide you with an excellent on-site support for installation, testing and more. - Reliable, robust and proven CE-IVD method
With our CE-IVD method you gain access to LC-MS/MS as the best available assay for an accurate steroid analysis. The parameters are determined directly without the risk of cross-reactivity as described for immunoassays. You can trust your test results with specific co-eluting internal standards, human-matrix based multilevel calibrators and MassCheck® controls.
Method of Analysis | LC-MS/MS |
---|---|
Number of Tests | 400 |
Please note | The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals. |
Lower Limit of Quantitation | 0.3 µg/l |
Upper Limit of Quantification | up to 120 μg/l (Cortisol) |
Intraassay | CV = 2–5 % |
Interassay | CV = 2–9 % |
Recovery | 96–105 % |
Specimen | Saliva |
Sample Preparation |
|
Run Time | 4.6 min |
Injection Volume | ≤ 30 µl |
Column Temperature | ambient (~ 25 °C) |
Gradient | binary |
Ionisation | ESI positive |
MS/MS Mode | MRM |
Parameters | Cortisol, Cortisone |
-
Analytical Column Cortisol, Cortisone in Saliva - LC-MS/MSOrder no.: 73100
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
6PLUS1® Multilevel Saliva Calibrator Set Cortisol, CortisoneOrder no.: 73040MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
MassCheck® Cortisol, Cortisone Saliva Controls (lyoph.)Order no.: 0353/0354
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
System Check Solution MassChrom® Steroid Panel 1Order no.: 72088
MassChrom® Steroids in Serum/Plasma - LC-MS/MS
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
6PLUS1® Multilevel Saliva Calibrator Set Cortisol, CortisoneOrder no.: 73040MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
MassCheck® Cortisol, Cortisone Saliva Controls (lyoph.)Order no.: 0353/0354
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS
-
Analytical Column Cortisol, Cortisone in Saliva - LC-MS/MSOrder no.: 73100
MassChrom® Cortisol, Cortisone in Saliva - LC-MS/MS