MassTox® TDM Series A
Modular System for Therapeutic Drug Monitoring
- 200 Parameters (continuously extended)
- 1 Analytical column – 1 sample prep
- Almost all parameters safeguarded by internal standards
- 3PLUS1® or 6PLUS1® Multilevel Calibrator Sets and MassCheck® plasma controls
- CSQUANT data mining software
- Robotic solution for more than 100 parameters with MassSTAR
The Three Components of MassTox® TDM Series A
Master Column
One analytical column for all. No column switching required.
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Basic Kit
Contains all components required for a complete sample preparation and all necessary mobile phases.
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Parameter Sets
Parameter menu of 200 analytes is divided in 13 parameter sets. All of them contain all relevant calibrators, quality controls and internal standards.
Example of a Parameter Set: MassTox® Neuroleptics 1/EXTENDED
Identical Sample Preparation for all Parameter Sets:
- Add 800 μl Internal Standard Mix to 12 ml Precipitation Reagent (= mixture A).
- Pipette 50 μl sample/calibrator/MassCheck® control
into a 1.5 ml reaction vial. - Add 25 μl Extraction Buffer, mix briefly (vortex)
and incubate 2 min. - Add 250 μl of mixture A, mix 30 s (vortex) and centrifuge 5 min.
- Dilute supernatant with Dilution Buffer (depending on instrument sensitivity) and inject into LC-MS/MS system.
The information on the sample preparation presented here is not sufficient for use in the laboratory. For a detailed step by step description, please refer to the instruction manual.
13 Parameter Sets available:
- Antiarrhythmic Drugs
- Antidepressants 1/EXTENDED
- Antidepressants 2/ Psychostimulants/ EXTENDED
- Antiepileptic Drugs All-in-One Method
- Anti-HIV Drugs
- Antimycotic Drugs
- Benzodiazepines 1
- Benzodiazepines 2
- Mycophenolic Acid
- Neuroleptics 1/EXTENDED
- Neuroleptics 2/EXTENDED 2
- Tricyclic Antidepressants TCA1
- Tricyclic Antidepressants TCA2
Parameter Menu
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