BASIC Kit A for 1000 tests with 96 Well Filter Plates

Basic Kit for all Parameters of TDM Series A

Antiarrhythmic Drugs (92923)

Acebutolol, Ajmaline, Amiodarone, Desethylamiodarone, Aprindine, Atenolol, Bisoprolol, Diltiazem, Disopyramide, Dronedarone, Debutyldronedarone, Flecainide, Flunarizine, Gallopamil, Lidocaine, Metoprolol, Mexiletine, Propafenone, Propranolol, Quinidine, Hydroquinidine, Sotalol, Tocainide, Verapamil, Norverapamil

Antidepressants 1/EXTENDED (92913/XT)

Citalopram, N-Desmethylcitalopram, Duloxetine, Fluoxetine, Desmethylfluoxetine, Fluvoxamine, Mirtazapine, N-Desmethylmirtazapine, Paroxetine, Sertraline, N-Desmethylsertraline, Venlafaxine, O-Desmethylvenlafaxine

Antidepressants 2/ Psychostimulants/EXTENDED (92915/XT)

Atomoxetine, Bupropion, Erythro-Dihydrobupropion, Threo-Dihydrobupropion, Hydroxybupropion, Clomethiazole, Dosulepin, N-Desmethyldosulepin, Methylphenidate, Mianserin, Milnacipran, Moclobemide, Opipramol, Reboxetine, Ritalinic acid, Tianeptine, Tranylcypromine, Trazodone, Vilazodone, Vortioxetine

Antiepileptic Drugs All-in-One Method (92921/XT)

Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, 10-OH-Carbamazepine, 10,11-Dihydroxycarbamazepine, Desmethylmesuximide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam, Oxcarbazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Phenytoin, Pregabalin, Primidone, Retigabine, Rufinamide, Stiripentol, Sultiame, Tiagabine, Theophylline, Topiramate, Valproic acid, Vigabatrin, Zonisamide

Anti-HIV Drugs (92924)

Amprenavir, Atazanavir, Darunavir, Delavirdine, Efavirenz, Elvitegravir, Etravirine, Indinavir, Lopinavir, Maraviroc, Nelfinavir, Nelfinavir-M8, Nevirapine, Raltegravir, Rilpivirine, Ritonavir, Saquinavir

Antimycotic Drugs/EXTENDED (92922/XT)

Amphotericin B*, Anidulafungin, Caspofungin, Fluconazole, 5-Flucytosine, Isavuconazole, Itraconazole, Hydroxyitraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole

Benzodiazepines 1 (92917)

Chlordiazepoxide, Clobazam, Norclobazam, Demoxepam, Diazepam, Nordiazepam, Medazepam, Midazolam, 1-OH-Midazolam, Oxazepam, Prazepam, Temazepam, Tetrazepam

Benzodiazepines 2 (92918)

Alprazolam, Bromazepam, Clonazepam, Flunitrazepam, Flurazepam, Desalkylflurazepam, Lorazepam, Lormetazepam, Nitrazepam, Triazolam

Mycophenolic Acid (92916)

Mycophenolic acid, Mycophenolic acid glucuronide

Neuroleptics 1/EXTENDED (92912/XT)

Aripiprazole, Dehydroaripiprazole, Clozapine, N-Desmethylclozapine, Haloperidol, Olanzapine, N-Desmethylolanzapine, Quetiapine, Norquetiapine, Risperidone, 9-OH-Risperidone

Neuroleptics 2/EXTENDED 2 (92914/XT2)

Amisulpride, Benperidol, Brexpiprazole, Bromperidol, Cariprazine, Chlorpromazine, Chlorprothixene, Flupentixol, Fluphenazine, Guanfacine, Iloperidone, Levomepromazine, Loxapine, Lurasidone, Melperone, Perazine, Perphenazine, Pimozide, Pipamperone, Promethazine, Prothipendyl, Sertindole, Sulforidazine, Sulpiride, Thioridazine, Ziprasidone, Zotepine, Zuclopenthixol

Tricyclic Antidepressants TCA1 (92919)

Amitriptyline, Desipramine, Doxepin, Nordoxepin, Imipramine, Nortriptyline

Tricyclic Antidepressants TCA2 (92920)

Clomipramine, Norclomipramine, Maprotiline, Normaprotiline, Protriptyline, Trimipramine, Nortrimipramine

* For Amphotericin B only qualitative information can be obtained, but data are not CE-IVD compliant.

Description

The Basic Kit A is a part of the Series A modular system, which enables the analysis of nearly 200 parameters without switching column or changing the mobile phases, thereby minimising the required workload in the laboratory. The Basic Kit A contains all components required for sample preparation and all necessary mobile phases.

This Chromsystems kit enables the automation of the Basic Kit.

In addition to the automated version Chromsystems also offers a standard version for manual processing of the Basic Kit A with 200 and 1000 tests.

Further component of the modular system is the MasterColumn® A, an analytical column used for the determination of all Series A analytes. Different Parameter Sets can be selected depending on the drug category – the portfolio covers 14 Parameter Sets for the determination of 200 substances and metabolites.

Content

3 x Mobile Phase 1 (92001)
3 x Mobile Phase 2 (92002)
5 x Extraction Buffer (92005)
5 x Dilution Buffer 1 (92007)
5 x Dilution Buffer 2 (92008)
2 x Rinsing Solution (92009)
1 x Precipitation Reagent (92012)
4 x 96 Well Filter Plates (92057)
8 x 96 Well Collection Plates (92058)
4 x Pierceable Adhesive Seals (92059

Technical Data

More Information
Method of Analysis	LC-MS/MS
Number of Tests	1000
Sample Preparation	Pipette 25 µl Extraktion Buffer into a 96 well filter plate (order no. 92057). Add 50 µl sample/calibrator/MassCheck® control. Shake 2 min (1200 rpm). Add 250 µl reconstituted Internal Standard Mix. Shake 40 s (700 rpm). Separate precipitate by centrifugation ( 2000 x g, 1 min) and collect the eluate in a collection plate (order no. 92058). Dilute eluate with Dilution Buffer, instrument and parameter set specific, in an additional collection plate. Seal collection plate with pierceable adhesive seal (order no. 92059) and transfer to autosampler. Inject eluate into the LC-MS/MS system.
Please note	The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals.
Parameter	200 grouped in 13 sets

Components

Mobile Phase 1
Order no.: 92001

MassTox^® TDM Series A

Details
Mobile Phase 2
Order no.: 92002

MassTox^® TDM Series A

Details
Extraction Buffer
Order no.: 92005

MassTox^® TDM Series A

Details
Dilution Buffer 1
Order no.: 92007

MassTox^® TDM Series A

Details
Dilution Buffer 2
Order no.: 92008

MassTox^® TDM Series A

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Rinsing Solution
Order no.: 92009

MassTox^® TDM Series A

Details
Precipitation Reagent
Order no.: 92012

MassTox^® TDM Series A

Details
96 Well Filter Plates
Order no.: 92057

MassTox^® TDM Series A

Details
96 Well Collection Plates
Order no.: 92058

MassTox^® TDM Series A

Details
Pierceable Adhesive Seals for 96 Well Plates
Order no.: 92059

MassTox^® TDM Series A

Details