6PLUS1® Multilevel Whole Blood Calibrator Set Immunosuppressants

Order No.: 28039
Parameters:
Cyclosporin A, Everolimus, Sirolimus, Tacrolimus
MassTox® Immunosuppressants in Whole Blood – LC-MS/MS

6PLUS1® Multilevel Calibrator Whole Blood Set Immunosuppressants, lyophilised

For MassTox® Immunosuppressants in Whole Blood by LC-MS/MS (93000, 93000/1200)

These lyophilised calibrators from Chromsystems are based on human whole blood and should be used according to the instruction manual. They are designed according to the recommendations of the FDA to calibrate the measurement method in clinical diagnostics for the quantitative determination of cyclosporin A, tacrolimus, sirolimus and everolimus in whole blood. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 6 different concentration levels plus 1 blank value.

More Information
Content 7 x 2 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance UnitCalibrator 1
(28031)
Calibrator 2
(28032)
Calibrator 3
(28033)
Calibrator 4
(28034)
Calibrator 5
(28035)
Calibrator 6
(28036)
Blank Calibrator
(28030)
Cyclosporin A (Ciclosporin) µg/l 25.3 125 301 476 800 971 n.d. (< 10)
Tacrolimus (FK 506) µg/l 1.5 5.82 11.9 17.2 24.3 41.6 n.d. (< 0.5)
Rapamycin (Sirolimus) µg/l 2.27 6.46 13.3 19.4 30.4 49.6 n.d. (< 1)
Everolimus µg/l 2.31 6.03 12.2 17.7 25.4 44.1 n.d. (< 1)

 n.d. = not detected (< LOQ)

The blank level is manufactured using the same matrix pool as used for the calibrator levels 1-6. It was not fortified with any immunosuppressants.

Method of Analysis LC-MS/MS
Parameters Cyclosporin A, Everolimus, Sirolimus, Tacrolimus

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.

6PLUS1® Multilevel Calibrator Whole Blood Set Immunosuppressants, lyophilised

For MassTox® Immunosuppressants in Whole Blood by LC-MS/MS (93000, 93000/1200)

These lyophilised calibrators from Chromsystems are based on human whole blood and should be used according to the instruction manual. They are designed according to the recommendations of the FDA to calibrate the measurement method in clinical diagnostics for the quantitative determination of cyclosporin A, tacrolimus, sirolimus and everolimus in whole blood. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 6 different concentration levels plus 1 blank value.

More Information
Content 7 x 2 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance UnitCalibrator 1
(28031)
Calibrator 2
(28032)
Calibrator 3
(28033)
Calibrator 4
(28034)
Calibrator 5
(28035)
Calibrator 6
(28036)
Blank Calibrator
(28030)
Cyclosporin A (Ciclosporin) µg/l 25.3 125 301 476 800 971 n.d. (< 10)
Tacrolimus (FK 506) µg/l 1.5 5.82 11.9 17.2 24.3 41.6 n.d. (< 0.5)
Rapamycin (Sirolimus) µg/l 2.27 6.46 13.3 19.4 30.4 49.6 n.d. (< 1)
Everolimus µg/l 2.31 6.03 12.2 17.7 25.4 44.1 n.d. (< 1)

 n.d. = not detected (< LOQ)

The blank level is manufactured using the same matrix pool as used for the calibrator levels 1-6. It was not fortified with any immunosuppressants.

Method of Analysis LC-MS/MS
Parameters Cyclosporin A, Everolimus, Sirolimus, Tacrolimus

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.