3PLUS1® Multilevel Plasma Calibrator Set Antidepressants 2/ Psychostimulants/EXTENDED

Order No.: 92027/XT
Parameters:
Atomoxetine, Bupropion, Clomethiazole, Dosulepin, erythro-Dihydrobupropion, Hydroxybupropion, Methylphenidate, Mianserin, Milnacipran, Moclobemide, N-Desmethyldosulepin, Opipramol, Ritalinic Acid, threo-Dihydrobupropion, Tianeptine, Tranylcypromine, Trazodone, Vilazodone, Vortioxetine
MassTox® TDM Series A Antidepressants 2/Psychostimulants/EXTENDED in Serum/Plasma – LC-MS/MS

Atomoxetine

Bupropion

erythro-Dihydrobupropion

Hydroxybupropion

threo-Dihydrobupropion

Clomethiazole

Dosulepin

N-Desmethyldosulepin

Methylphenidate

Mianserin

Milnacipran

Moclobemide

Opipramol

Reboxetine

Ritalinic acid

Tianeptine

Tranylcypromine

Trazodone

Vilazodone

Vortioxetine

3PLUS1® Multilevel Plasma Calibrator Set Antidepressants 2/Psychostimulants/EXTENDED

For MassTox® TDM Series A Parameter Set Antidepressants 2/Psychostimulants/EXTENDED in Serum/Plasma by LC-MS/MS (92915/XT)

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of antidepressants 2 and psychostimulants/EXTENDED in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 3 different concentration levels plus 1 blank value.

More Information
Content 4 x 1 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

NEW: An Excel file with the data from the product information leaflet is now available in the "Downloads" section (for registered customers only). This eliminates manual data entry of large data sets.

Substance Calibrator 1
(µg/l)
Calibrator 2
(µg/l)
Calibrator 3
(µg/l)
Blank Calibrator
(µg/l)
Atomoxetine 23.7 638 1204 n.d. (<2.58)
Clomethiazole 56.4 2509 4796 n.d. (<19.4)
Dosulepin 70.0 150 228 n.d. (<8.40)
N-Desmethyldosulepin 14.2 190 364 n.d. (<3.56)
Methylphenidate 3.29 42.1 78.6 n.d. (<0.805)
Mianserin 6.92 91.6 168 n.d. (<2.23)
Milnacipran 19.6 206 368 n.d. (<5.53)
Moclobemide 154 1367 2453 n.d. (<41.4)
Opipramol 36.7 320 594 n.d. (<9.96)
Reboxetine 21.2 215 411 n.d. (<5.81)
Ritalinic Acid 27.6 189 344 n.d. (<7.22)
Tianeptine 21.1 181 350 n.d. (<11.3)
Tranylcypromine 7.53 306 615 n.d. (<5.11)
Trazodone 230 1637 2891 n.d. (<115)
Vilazodone 23.1 57.7 91.0 n.d. (<7.41)
Vortioxetine 6.92 49.8 92.8 n.d. (<4.11)
Bupropion 6.74 154 301 n.d. (<1.83)
erythro-Dihydrobupropion 6.73 148 291 n.d. (<3.90)
Hydroxybupropion 29.0 1055 2060 n.d. (<7.38)
threo-Dihydrobupropion 34.9 746 1377 n.d. (<2.70)

n.d. = not detected (< LOQ)
The blank level is manufactured using the same matrix pool as used for the calibrator levels 1, 2 and 3. It was not fortified with any drugs.

Method of Analysis LC-MS/MS
Parameters Atomoxetine, Bupropion, Clomethiazole, Dosulepin, erythro-Dihydrobupropion, Hydroxybupropion, Methylphenidate, Mianserin, Milnacipran, Moclobemide, N-Desmethyldosulepin, Opipramol, Ritalinic Acid, threo-Dihydrobupropion, Tianeptine, Tranylcypromine, Trazodone, Vilazodone, Vortioxetine

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.

Atomoxetine

Bupropion

erythro-Dihydrobupropion

Hydroxybupropion

threo-Dihydrobupropion

Clomethiazole

Dosulepin

N-Desmethyldosulepin

Methylphenidate

Mianserin

Milnacipran

Moclobemide

Opipramol

Reboxetine

Ritalinic acid

Tianeptine

Tranylcypromine

Trazodone

Vilazodone

Vortioxetine

3PLUS1® Multilevel Plasma Calibrator Set Antidepressants 2/Psychostimulants/EXTENDED

For MassTox® TDM Series A Parameter Set Antidepressants 2/Psychostimulants/EXTENDED in Serum/Plasma by LC-MS/MS (92915/XT)

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of antidepressants 2 and psychostimulants/EXTENDED in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 3 different concentration levels plus 1 blank value.

More Information
Content 4 x 1 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

NEW: An Excel file with the data from the product information leaflet is now available in the "Downloads" section (for registered customers only). This eliminates manual data entry of large data sets.

Substance Calibrator 1
(µg/l)
Calibrator 2
(µg/l)
Calibrator 3
(µg/l)
Blank Calibrator
(µg/l)
Atomoxetine 23.7 638 1204 n.d. (<2.58)
Clomethiazole 56.4 2509 4796 n.d. (<19.4)
Dosulepin 70.0 150 228 n.d. (<8.40)
N-Desmethyldosulepin 14.2 190 364 n.d. (<3.56)
Methylphenidate 3.29 42.1 78.6 n.d. (<0.805)
Mianserin 6.92 91.6 168 n.d. (<2.23)
Milnacipran 19.6 206 368 n.d. (<5.53)
Moclobemide 154 1367 2453 n.d. (<41.4)
Opipramol 36.7 320 594 n.d. (<9.96)
Reboxetine 21.2 215 411 n.d. (<5.81)
Ritalinic Acid 27.6 189 344 n.d. (<7.22)
Tianeptine 21.1 181 350 n.d. (<11.3)
Tranylcypromine 7.53 306 615 n.d. (<5.11)
Trazodone 230 1637 2891 n.d. (<115)
Vilazodone 23.1 57.7 91.0 n.d. (<7.41)
Vortioxetine 6.92 49.8 92.8 n.d. (<4.11)
Bupropion 6.74 154 301 n.d. (<1.83)
erythro-Dihydrobupropion 6.73 148 291 n.d. (<3.90)
Hydroxybupropion 29.0 1055 2060 n.d. (<7.38)
threo-Dihydrobupropion 34.9 746 1377 n.d. (<2.70)

n.d. = not detected (< LOQ)
The blank level is manufactured using the same matrix pool as used for the calibrator levels 1, 2 and 3. It was not fortified with any drugs.

Method of Analysis LC-MS/MS
Parameters Atomoxetine, Bupropion, Clomethiazole, Dosulepin, erythro-Dihydrobupropion, Hydroxybupropion, Methylphenidate, Mianserin, Milnacipran, Moclobemide, N-Desmethyldosulepin, Opipramol, Ritalinic Acid, threo-Dihydrobupropion, Tianeptine, Tranylcypromine, Trazodone, Vilazodone, Vortioxetine

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.