Vitamin A/E

Title Summary Year
Vitamin A Plasma Levels in COVID-19 Patients: A Prospective
Multicenter Study and Hypothesis
Vitamin A plasma levels in COVID-19 patients are reduced during acute inflammation and that severely reduced plasma levels of vitamin A are significantly associated with Acute Respiratory Distress Syndrome and mortality. Vitamin A was measured with Chromsystems HPLC assay. 2021
Dynamics of Serum Retinol and Alpha-Tocopherol Levels According to Non-Alcoholic Fatty Liver Disease Status While circulating concentrations of retinol and α-tocopherol were positively associated with the presence of non-alcoholic fatty liver disease advanced liver fibrosis was only correlated with serum retinol levels. Vitamin A and E were measured with the Chromsystems HPLC assay. 2021
Effects of Antioxidant Vitamins, Curry Consumption, and Heavy Metal Levels on Metabolic Syndrome with Comorbidities: A Korean Community-Based Cross-Sectional Study Vitamins and curry supplements might reduce the prevalence of metabolic syndrome. The results indicate that thiamine and curry intakes might protect the public against the dual burden of communicable and non-communicable diseases in Korea. However, further work is required to determine the nature of the mechanisms involved. Vitamin A and E were measured with Chromsystems HPLC assay. 2021
Negative Correlation Between Vitamin A and Positive Correlation Between Vitamin E and Inflammation Among Healthy Adults in Korea: Based on the Korea National Health and Nutrition Examination Survey (KNHANES) 2016–2018 7th Edition Vitamins exert its effect through different isoforms. The isoform conversion phases involved are affected outside factors. Here, we investigated the correlation between serum retinol, α-tocopherol, and serum inflammatory markers using stratified data acquired from 2016 to 2018 Korea National Health and Nutrition Examination Survey (KNHANES). Vitamin A and E are measured with the Chromsystems HPLC assay in this study 2020
Antioxidant Activity with Increased Endogenous Levels of Vitamin C, E and A Following Dietary Supplementation with a Combination of Glutathione and Resveratrol Precursors This study provides preliminary evidence for the use of GSH precursors combined with polydatin to maintain redox status into an ideal range. Chromsystems assays were used for the determination of vitamin A/E/C 2020
Association Between Serum Retinol and α-Tocopherol Levels and Metabolic Syndrome in Korean General Population: Analysis of Population-based Nationally Representative Data high serum retinol and α-tocopherol levels were associated with increased risk of metabolic syndrome. Vitamin A and E were measured with Chromsystems HPLC assay.  2020
Patisiran Pharmacokinetics, Pharmacodynamics, and Exposure‐Response Analyses in the Phase 3 APOLLO Trial in Patients With Hereditary Transthyretin‐Mediated (hATTR) Amyloidosis The patisiran dosing regimen of 0.3 mg/kg every 3 weeks is appropriate for all patients with hATTR amyloidosis. A measured with HPLC assay from Chromsystems. 2020
Assessment of Vitamin Status in Patients with Nontuberculous Mycobacterial Pulmonary Disease: Potential Role of Vitamin A as a Risk Factor Their study suggests that altered vitamin status is associated with mycobacterial disease, and that vitamin A might play an important role in nontuberculous mycobacterial pulmonary disease.  The analysis of vitamin A/E was performed by the HPLC assay from Chromsystems. 2019
Impact of HSD17B13 rs72613567 genotype on hepaticdecompensation and mortality in patients with portalhypertension In patients with viral hepatitis‐ and ALD‐induced portal hypertension, the T > TA‐variant was not protective of hepatic decompensation and mortality. Further studies should investigate the pathophysiological mechanisms underlying the effects of HSD17B13 genotype at different stages of liver disease. 2019
Oxidized and electronegative low-density lipoprotein as potential biomarkers of cardiovascular risk in obese adolescents Obese adolescents showed increased plasma LDL(-) and oxLDL, and obese girls had more LDL(-) than obese boys. Therefore, oxLDL is strongly and independently associated with classical cardiovascular risk factors, while increased levels of LDL(-) were influenced by body mass index, waist circumference and demographic parameters in obese adolescents. antioxidants all measured by Chromsystems assays. 2018
Vitamin A Status in Healthy Women Eating Traditionally Prepared Spirulina (Dihé) in the Chad Lake Area We demonstrate that β-carotene in spirulina is an effective positive modulator of blood retinol status and that a natural food compound, Dihè, is a potential natural source of β-carotene to achieve an optimal vitamin A status in healthy women. Vitamin A and ß-carotene measured by Chromsystems assay. 2018
Vitamin A Status in Healthy Women Eating Traditionally Prepared Spirulina (Dihé) in the Chad Lake Area The results confirm that β-carotene in spirulina is an effective positive modulator of blood retinol status. Dihé is a potential natural source of β-carotene to achieve a proper vitamin A status in healthy women living near Chad Lake.. Vitamin A and β-Carotene by Chromsystems HPLC assay. 2018
Hyperphenylalaninemia Correlated with Global Decrease of Antioxidant Genes Expression in White Blood Cells of Adult Patients with Phenylketonuria This study is the first to evaluate the expression of 22 antioxidant genes in white blood cells regarding biochemical parameters in PKU. Vitamin A, C and E measured with Chromsystems assays. 2017
Alpha-tocopherol and MRI outcomes in multiple sclerosis--association and prediction The authors show an association between increasing alpha-tocopherol concentrations and simultaneous and subsequent MRI disease activity in multiple sclerosis patients during treatment with IFNB. Tocopherol was measured by Chromsystems HPLC assay. 2013
Is There a Relationship Between Serum Levels of Vitamin A, Vitamin E, Copper and Zinc and Otitis Media With Effusion in Children? The results of this study showed that serum levels of vitamin A, vitamin E and copper may not play a role on development of OME. On the other hand, we found that the serum levels of zinc were higher in group 2 patients (adenoid hyperplasia-alone) than group 1 patients (OME-adenoid hyperplasia).  Vitamin A and E were measured by Chromsystems assay. 2012
Antioxidant defense and oxidative stress in children with acute hepatitis A Their research points out that hepatatis A infection causes oxidative stress in children. Antioxidant vitamin supplements could be added to the therapy for these patients to help reestablish the oxidant status balance. However, further investigations to confirm this suggestion are recommended. Ascorbic acid, α-tocopherol, retinol, β-carotene, and GSH, Malondialdehyde measured with Chromsystems assay . 2011
Correlation Between Vitamin A, E, Coenzyme Q(10) and Degree of Insulin Resistance in Obese and Non-Obese Subjects The study shows no significant correlations between serum coenzyme Q(10), plasma vitamin A and E levels and insulin resistance in obese and control subjects. 2011
The vitamin E-binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis The auhtors found differences in peritoneal fluid  afamin levels between women with and without endometriosis, a finding that confirms the link between the disease and localized oxidative stress. Vitamin E measured by HPLC 2010
Vitamin A status of healthy children in Manisa, Turkey This study showed that vitamin a deficiency is a moderate health problem in Manisa. 2010
alpha-Tocopherol Disturbs Macrophage LXRalpha Regulation of ABCA1/G1 and Cholesterol Handling alpha-Tocopherol compromises cellular lipid scavenging and channelling of cholesterol into reverse transport out of the vessel wall. The determination in cell cultures was taking place with the Chromsystems assay 2008
Vitamin A and beta-carotene supply of women with gemini or short birth intervals: a pilot study Despite the fact that vitamin A and beta-carotene rich food is generally available, risk groups for low vitamin A supply exist in the western world. Both vitamins measured by Chromsystems HPLC assays. 2007

Please find here publications as guides for reference ranges or therapeutic ranges. As they may differ from other published data. Data vary depending on patient population and measurement method, please determine ranges for your laboratory. When determining ranges make sure that you comply with local national requirements. 

Title Summary  Year
Gressner A.M., Arndt T. (Eds). Lexikon der Medizinischen Laboratoriumsdiagnostik, 3rd edition, Springer Verlag (2019).   Book with reference values 2019
Soldin SJ, Wang, et al. Pediatric Refrence Intervals: 7th edition, AACC Press (2011) Book with reference values 2011