Endocrine Plasma Controls

Order No.: 0010/0020
Parameters:
3,4-Dihydroxymandelic Acid (DOMA), 3,4-Dihydroxyphenylacetic Acid(DOPAC), 3,4-Dihydroxyphenylalanine (L-DOPA), 3,4-Dihydroxyphenylglycol (DHPG), 3-Methoxy-4-hydroxyphenylglycol (MHPG), 3-Methoxytyramine, 5-Hydroxyindoleacetic Acid (5-HIAA), Adrenaline (Epinephrine), Dopamine, Homovanillic Acid (HVA), Metanephrine, Noradrenaline, Normetanephrine, Serotonin, Vanillylmandelic Acid (VMA)

For Biogenic Amines in Plasma - HPLC

Grouped product items
Product Name Qty
Endocrine Plasma Control, normal range
Order No.: 0010
Endocrine Plasma Control, pathological range
Order No.: 0020

3,4-Dihydroxymandelic Acid (DOMA)

3,4-Dihydroxyphenylacetic Acid (DOPAC)

3,4-Dihydroxyphenylalanine (L-DOPA)

3,4-Dihydroxyphenylglycol (DHPG)

3-Methoxy-4-hydroxyphenylglycol (MHPG)

3-Methoxytyramine

5-Hydroxyindoleacetic Acid (5-HIAA)

Adrenaline (Epinephrine)

Dopamine

Homovanillic Acid (HVA)

Metanephrine

Noradrenaline

Normetanephrine

Serotonin

Vanillylmandelic Acid (VMA)

Endocrine Plasma Controls, lyophilised

0010 Endocrine Plasma Control, Normal Range (lyoph.), 10 x 5 ml
0020 Endocrine Plasma Control, Pathological Range (lyoph.), 10 x 5 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of endocrine hormones and their metabolites in plasma. Further values are related to parameters for neurochemical analyses. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

More Information
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

SubstanceMethodUnitValueRangeValueRange
      Normal Range Pathological Range
Catecholamines
Noradrenaline HPLC ng/l
pmol/l
269
1587
188-349
1111-2063
2012
11892
1509-2515
8919-14865
Adrenaline HPLC ng/l
pmol/l
108
589
75,5-140
412-766
477
2605
358-596
1953-3256
Dopamine HPLC ng/l
pmol/l
176
1150
123-229
805-1495
848
5536
593-1102
3875-7197
Serotonin HPLC µg/l
nmol/l
146
829
117-175
663-994
347
1968
278-417
1574-2362
Metanephrines
Metanephrine spiked value ng/l
pmol/l
60
304
48-72
243-365
1500
7605
1200-1800
6084-9126
Normetanephrine spiked value ng/l
pmol/l
100
546
80-120
437-655
7000
38220
5600-8400
30576-45864
3-Methoxytyramine spiked value       1500
8970
1200-1800
7176-10764
Vanillylmandelic acid
(VMA)
spiked value µg/l
nmol/l
7.5
37.8
6.0-9.0
30.2-45.4
80.1
403
64.0-96.0
323-484
Homovanillic acid
(HVA)
spiked value µg/l
nmol/l
10
54.9
8-12
43.9-65.9
100,0
549
80.1-120.0
440-659
5-Hydroxyindole-3-acetic acid
(5-HIAA)
spiked value µg/l
nmol/l
8.0
41.8
6.4-9.6
33.5-50.2
40.0
209
32.0-48.0
167-251

3,4-Dihydroxyphenyl-acetic acid (DOPAC)

spiked value µg/l
nmol/l
4.0
23.8
3.2-4.8
19.0-28.5
55.0
326
44.0-66.0
261-392
3-Methoxy-4-hydroxy-phenylglycol (MHPG) spiked value µg/l
nmol/l
5.0
27.1
4.0-6.0
21.7-32.5
30.0
163
24.0-36.0
130-195
3,4-Dihydroxyphenyl-glycol (DHPG) spiked value µg/l
nmol/l
3.0
17.6
2.4-3.6
14.1-21.2
15.0
88.2
12.0-18.0
70.6-106
3,4-Dihydroxymandelic acid (DOMA) spiked value µg/l
nmol/l
0.80
4.34
0.64-0.96
3.5-5.2
5.0
27.2
4.0-6.0
21.7-32.6
3,4-Dihydroxyphenyl-alanine (L-DOPA) spiked value µg/l
nmol/l
1.5
7.61
1.2-1.8
6.08-9.13
6.0
30.4
4.8-7.2
24.3-36.5
Storage conditions

Stored at +2 to +8 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 2 days light protected and tightly capped at +2 to +8 C. The reconstituted controls have the same stability as a fresh plasma specimen. Since the different parameters of these plasma controls have different stability characteristics in solution, the specific storage conditions for the individual parameters should also be selected for the controls. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 2 months). For more details about storage conditions please check your instruction manual.

Method of Analysis HPLC
Parameter 3,4-Dihydroxymandelic Acid (DOMA), 3,4-Dihydroxyphenylacetic Acid(DOPAC), 3,4-Dihydroxyphenylalanine (L-DOPA), 3,4-Dihydroxyphenylglycol (DHPG), 3-Methoxy-4-hydroxyphenylglycol (MHPG), 3-Methoxytyramine, 5-Hydroxyindoleacetic Acid (5-HIAA), Adrenaline (Epinephrine), Dopamine, Homovanillic Acid (HVA), Metanephrine, Noradrenaline, Normetanephrine, Serotonin, Vanillylmandelic Acid (VMA)
As a customer please login or register to gain full access.

3,4-Dihydroxymandelic Acid (DOMA)

3,4-Dihydroxyphenylacetic Acid (DOPAC)

3,4-Dihydroxyphenylalanine (L-DOPA)

3,4-Dihydroxyphenylglycol (DHPG)

3-Methoxy-4-hydroxyphenylglycol (MHPG)

3-Methoxytyramine

5-Hydroxyindoleacetic Acid (5-HIAA)

Adrenaline (Epinephrine)

Dopamine

Homovanillic Acid (HVA)

Metanephrine

Noradrenaline

Normetanephrine

Serotonin

Vanillylmandelic Acid (VMA)

Endocrine Plasma Controls, lyophilised

0010 Endocrine Plasma Control, Normal Range (lyoph.), 10 x 5 ml
0020 Endocrine Plasma Control, Pathological Range (lyoph.), 10 x 5 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of endocrine hormones and their metabolites in plasma. Further values are related to parameters for neurochemical analyses. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

More Information
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

SubstanceMethodUnitValueRangeValueRange
      Normal Range Pathological Range
Catecholamines
Noradrenaline HPLC ng/l
pmol/l
269
1587
188-349
1111-2063
2012
11892
1509-2515
8919-14865
Adrenaline HPLC ng/l
pmol/l
108
589
75,5-140
412-766
477
2605
358-596
1953-3256
Dopamine HPLC ng/l
pmol/l
176
1150
123-229
805-1495
848
5536
593-1102
3875-7197
Serotonin HPLC µg/l
nmol/l
146
829
117-175
663-994
347
1968
278-417
1574-2362
Metanephrines
Metanephrine spiked value ng/l
pmol/l
60
304
48-72
243-365
1500
7605
1200-1800
6084-9126
Normetanephrine spiked value ng/l
pmol/l
100
546
80-120
437-655
7000
38220
5600-8400
30576-45864
3-Methoxytyramine spiked value       1500
8970
1200-1800
7176-10764
Vanillylmandelic acid
(VMA)
spiked value µg/l
nmol/l
7.5
37.8
6.0-9.0
30.2-45.4
80.1
403
64.0-96.0
323-484
Homovanillic acid
(HVA)
spiked value µg/l
nmol/l
10
54.9
8-12
43.9-65.9
100,0
549
80.1-120.0
440-659
5-Hydroxyindole-3-acetic acid
(5-HIAA)
spiked value µg/l
nmol/l
8.0
41.8
6.4-9.6
33.5-50.2
40.0
209
32.0-48.0
167-251

3,4-Dihydroxyphenyl-acetic acid (DOPAC)

spiked value µg/l
nmol/l
4.0
23.8
3.2-4.8
19.0-28.5
55.0
326
44.0-66.0
261-392
3-Methoxy-4-hydroxy-phenylglycol (MHPG) spiked value µg/l
nmol/l
5.0
27.1
4.0-6.0
21.7-32.5
30.0
163
24.0-36.0
130-195
3,4-Dihydroxyphenyl-glycol (DHPG) spiked value µg/l
nmol/l
3.0
17.6
2.4-3.6
14.1-21.2
15.0
88.2
12.0-18.0
70.6-106
3,4-Dihydroxymandelic acid (DOMA) spiked value µg/l
nmol/l
0.80
4.34
0.64-0.96
3.5-5.2
5.0
27.2
4.0-6.0
21.7-32.6
3,4-Dihydroxyphenyl-alanine (L-DOPA) spiked value µg/l
nmol/l
1.5
7.61
1.2-1.8
6.08-9.13
6.0
30.4
4.8-7.2
24.3-36.5
Storage conditions

Stored at +2 to +8 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 2 days light protected and tightly capped at +2 to +8 C. The reconstituted controls have the same stability as a fresh plasma specimen. Since the different parameters of these plasma controls have different stability characteristics in solution, the specific storage conditions for the individual parameters should also be selected for the controls. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 2 months). For more details about storage conditions please check your instruction manual.

Method of Analysis HPLC
Parameter 3,4-Dihydroxymandelic Acid (DOMA), 3,4-Dihydroxyphenylacetic Acid(DOPAC), 3,4-Dihydroxyphenylalanine (L-DOPA), 3,4-Dihydroxyphenylglycol (DHPG), 3-Methoxy-4-hydroxyphenylglycol (MHPG), 3-Methoxytyramine, 5-Hydroxyindoleacetic Acid (5-HIAA), Adrenaline (Epinephrine), Dopamine, Homovanillic Acid (HVA), Metanephrine, Noradrenaline, Normetanephrine, Serotonin, Vanillylmandelic Acid (VMA)
As a customer please login or register to gain full access.