6PLUS1® Multilevel Plasma Calibrator Set Anti-HIV Drugs

Order No.: 92053

Parameters:

Amprenavir, Atazanavir, Darunavir, Delavirdine, Efavirenz, Elvitegravir, Etravirine, Indinavir, Lopinavir, Maraviroc, Nelfinavir, Nelfinavir-M8, Nevirapine, Raltegravir, Rilpivirine, Ritonavir, Saquinavir

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Parameters

Description

Technical Data

Downloads

Amprenavir

Atazanavir

Darunavir

Delavirdine

Efavirenz

Elvitegravir

Etravirine

Indinavir

Lopinavir

Maraviroc

Nelfinavir

Nelfinavir-M8

Nevirapine

Raltegravir

Rilpivirine

Ritonavir

Saquinavir

6PLUS1® Multilevel Plasma Calibrator Set Anti-HIV Drugs, lyophilised
Related MassTox® TDM Series A Parameter Set: Anti-HIV Drugs in Serum/Plasma (92924)

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of anti-HIV drugs in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 6 different concentration levels plus 1 blank value.

More Information

Content

7 x 1 ml (lyoph.)

Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

NEW: An Excel file with the data from the product information leaflet is now available in the "Downloads" section (for registered customers only). This eliminates manual data entry of large data sets.

Substance	Calibrator 1 (µg/l)	Calibrator 2 (µg/l)	Calibrator 3 (µg/l)	Calibrator 4 (µg/l)	Calibrator 5 (µg/l)	Calibrator 6 (µg/l)	Blank Calibrator (µg/l)
Group 1
Amprenavir	203	729	1239	1772	2272	2793	n.d. (< 10.0)
Darunavir	48.4	1159	2277	3359	4475	5531	n.d. (< 12.0)
Delavirdine	683	3060	5294	7510	9897	11793	n.d. (< 6.0)
Maraviroc	26.9	289	547	807	1071	1315	n.d. (< 2.0)
Nevirapine	1941	3067	4168	5387	6482	7653	n.d. (< 20)
Raltegravir	27.6	158	282	407	537	663	n.d. (< 7.0)
Group 2
Efavirenz	638	1463	2283	3138	3962	4771	n.d. (< 65)
Indinavir	7.86	751	1495	2197	2894	3533	n.d. (< 2.0)
Nelfinavir	541	1023	1504	1978	2437	2875	n.d. (< 2.0)
M8-Nelfinavir	164	514	850	1204	1536	1855	n.d. (< 1.0)
Rilpivirine	37.2	115	187	260	333	403	n.d. (< 5.0)
Saquinavir	35.0	222	404	590	774	954	n.d. (< 3.0)
Group 3
Atazanavir	60.2	733	1379	2049	2652	3324	n.d. (< 3.0)
Elvitegravir	135	350	571	793	1015	1238	n.d. (< 10)
Etravirine	55.5	639	1211	1794	2347	2931	n.d. (< 20)
Lopinavir	733	2943	5073	7224	9236	11161	n.d. (< 4.0)
Ritonavir	187	2970	5610	8172	10470	12587	n.d. (< 8.0)

n.d. = not determined (< LOQ)
The blank level is manufactured using the same matrix pool as used for the calibrator levels 1-6. It was not fortified with any Anti-HIV drugs.

Storage conditions

Stored below -18 °C and unopened, the lyophilised calibrators are stable until the expiry date specified on the vial labels. The reconstituted calibrators can be stored in glass containers up to 2 weeks light protected and tightly capped at +2 to +8 C. If the calibrators cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.

Method of Analysis

LC-MS/MS

Parameter

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