MassSTAR - automated assays
- Walkaway solution with standardised hardware and software
- Graphical user interface (GUI) for simple handling
- Test menu frequently updated and expanded
MassSTAR is designed for automating clinical LC-MS/MS and HPLC sample preparation with Chromsystems assays.
The solution has been developed with clinical laboratories in mind, offering the necessary flexibility and great user comfort.
Optimised applications for MassSTAR
Automated sample preparation for vitamins A and E by HPLC
- Supports multiple tube types within a single run
- Processes up to 93 samples per run, plus calibrator and two controls
- Allows premature unloading of reagents
- Provides target values for calibrators and quality controls in batch files
- Option to use HPLC columns at ambient temperature or at 35 °C
- No cooling of eluates required
- No precolumn necessary
- No UHPLC needed
- Short run time of under 3 minutes
The assay allows for the simultaneous quantitative determination of vitamin A (retinol) and vitamin E (α-tocopherol) in human serum or plasma samples by HPLC. Analytes are released from their transport proteins or lipoproteins through precipitation. They are then chromatographically separated in a single isocratic HPLC run and quantified using a UV detector.
A dedicated application for the Chromsystems MassSTAR is available for automated sample preparation using 96 deep well plates, ensuring efficient and accurate sample processing.
Automated sample preparation for vitamins B1 and B6 by (U)HPLC
- Supports multiple tube types within a single run
- Processes up to 93 samples per run, plus calibrator and two controls
- Allows premature unloading of reagents
- Provides target values for calibrators and quality controls in batch file
- Internal standard for each parameter
- High sample throughput
- No post-column derivatisation required
- For HPLC and UHPLC
The assay enables simultaneous determination of the active forms of vitamin B1 (TPP) and vitamin B6 (PLP) in human whole blood using HPLC or UHPLC. During sample preparation, analytes are derivatised, eliminating the need for traditional post-column derivatisation. The substances are then chromatographically separated using a binary gradient in either HPLC or UHPLC.
A dedicated Chromsystems MassSTAR application enables automated sample preparation, ensuring efficient, accurate processing and significantly reducing hands-on time.
Do you have any questions or want to learn more?
For more information about these new automated applications please contact your local sales representative.
The complete MassSTAR testing menu
MassTox® TDM Series A
Antidepressants 1/EXTENDED (order no. 92713/XT)
Citalopram, N-Desmethylcitalopram, Duloxetine, Fluoxetine, Desmethylfluoxetine, Fluvoxamine, Mirtazapine, N-Desmethylmirtazapine, Paroxetine, Sertraline, N-Desmethylsertraline, Venlafaxine, O-Desmethylvenlafaxine
Antidepressants 2/Psychostimulants/EXTENDED (order no. 92715/XT)
Atomoxetine, Bupropion, Erythro-Dihydrobupropion, Threo-Dihydrobupropion, Hydroxybupropion, Clomethiazole, Dosulepin, N-Desmethyldosulepin, Methylphenidate, Mianserin, Milnacipran, Moclobemide, Opipramol, Reboxetine, Ritalinic acid, Tianeptine, Tranylcypromine, Trazodone, Vilazodone, Vortioxetine
Antiepileptic Drugs All-in-One Method (order no. 92721/XT)
Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, 10-OH-Carbamazepine, 10,11-Dihydroxycarbamazepine, N-Desmethylmesuximide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam, Oxcarbazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Phenytoin, Pregabalin, Primidone, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic acid, Vigabatrin, Zonisamide
Antimycotic Drugs/EXTENDED (order no. 92722/XT)
Anidulafungin, Caspofungin, Fluconazole, 5-Flucytosine, Isavuconazole, Itraconazole, Hydroxyitraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole
Mycophenolic Acid (order no. 92716)
Mycophenolic acid, Mycophenolic acid glucuronide
Neuroleptics 1/EXTENDED (order no. 92712/XT)
Aripiprazole, Dehydroaripiprazole, Clozapine, N-Desmethylclozapine, Haloperidol, Olanzapine, N-Desmethylolanzapine, Quetiapine, Norquetiapine, Risperidone, 9-OH-Risperidone
Neuroleptics 2/EXTENDED 2 (order no. 92714/XT2)
Amisulpride, Benperidol, Brexpiprazole, Bromperidol, Cariprazine, Chlorpromazine, Chlorprothixene, Flupentixol, Fluphenazine, Guanfacine, Iloperidone, Levomepromazine, Loxapine, Lurasidone, Melperone, Perazine, Perphenazine, Pimozide, Pipamperone, Promethazine, Prothipendyl, Sertindole, Sulforidazine, Sulpiride, Thioridazine, Ziprasidone, Zotepine, Zuclopenthixol
MassTox® Immunosuppressants
Cyclosporin A, Everolimus, Sirolimus, Tacrolimus
MassChrom® Vitamin D
25-OH-Vitamin D2, 25-OH-Vitamin D3
Instrumentation and assays are supported by the Chromsystems scientific support team with extensive experience in automated clinical LC-MS/MS and HPLC.
Webinar: Automation of LC-MS/MS and HPLC workflows in clinical diagnostics
You learn how automation can improve the efficiency, accuracy and reliability of laboratory workflows. Key features include ease of use, precision, high throughput and traceability.
Webinar: Automation in Therapeutic Drug Monitoring with MassSTAR
Dr. Maximilian Dietz, Research & Development Manager at Chromsystems talks in this recorded webinar about the full CE-IVD walkaway solution MassStar that automates sample preparation in TDM.
These products are not available in all countries.
Download Brochure
You would like to learn more about MassSTAR? Then you are welcome to download our brochure. After you have filled out the following form, the respective links to download your documents will be sent to the e-mail address provided.
