MassCheck® Antiepileptic Drugs/EXTENDED Plasma Controls

Order No.: 0249/XT; 0250/XT; 0251/XT
Parameters:
10,11-Dihydroxycarbamazepine, 10-OH-Carbamazepine, Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam (Keppra®), N-Desmethylmesuximide, Oxcarbamazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Pregabalin, Primidone, Retigabine, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic Acid, Zonisamide

MassTox® TDM Series A Antiepileptic Drugs in Serum/Plasma – LC-MS/MS

Grouped product items
Product Name Qty
MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Bi-Level (I+II)
Order No.: 0249/XT
MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level I
Order No.: 0250/XT
MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level II
Order No.: 0251/XT

Brivaracetam

Carbamazepine

Carbamazepine-10,11-epoxide

10,11-Dihydroxycarbamazepine

10-OH-Carbamazepine

Oxcarbamazepine

Ethosuximide

Felbamate

Gabapentin

Lacosamide

Lamotrigine

Levetiracetam (Keppra®)

N-Desmethylmesuximide

Perampanel

Phenobarbital

Phenylethylmalonamide (PEMA)

Phenytoin

Pregabalin

Primidone

Retigabine

Rufinamide

Stiripentol

Sultiame

Theophylline

Tiagabine

Topiramate

Valproic acid

Vigabatrin

Zonisamide

MassCheck® Antiepileptic Drugs/EXTENDED Plasma Controls

For MassTox® TDM Series A Parameter Sets by LC-MS/MS:
Antiepileptic Drugs in Serum/Plasma (92921)
Antiepileptic Drugs All-in-One-Methode in Serum/Plasma (92921/XT)

0249/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0250/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level I (lyoph.), 5 x 1 ml
0251/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of antiepileptic drugs in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

More Information
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

NEW: An Excel file with the data from the product information leaflet is now available in the "Downloads" section (for registered customers only). This eliminates manual data entry of large data sets.

Substance

Target value

Level I

Target range

Level I

Target value

Level II

Target range

Level II

10-OH-Carbamazepine

7.80

6.24-9.36

33.9

27.1-40.7

Carbamazepine

3.17

2.54-3.8

10.6

8.48-12.7

Carbamazepine-10.11-epoxide

1.14

0.912-1.37

7.68

6.14-9.22

Carbamazepine-Diol

0.978

0.782-1.17

8.34

6.67-10

Oxcarbazepine

0.402

0.322-0.482

2.81

2.25-3.37

Felbamate

25.1

20.1-30.1

89.3

71.4-107

Lacosamide

1.84

1.47-2.21

8.28

6.62-9.94

Lamotrigine

3.21

2.57-3.85

12.7

10.2-15.2

Levetiracetam

16.6

13.3-19.9

68.3

54.6-82

Rufinamide

7.83

6.26-9.4

25.8

20.6-31

Theophylline

9.38

7.5-11.3

18.8

15-22.6

Gabapentin

4.13

3.3-4.96

19.4

15.5-23.3

Pregabalin

1.15

0.92-1.38

8.91

7.13-10.7

Sultiame

1.71

1.37-2.05

11.1

8.88-13.3

Tiagabine (in µg/l)

34.9

27.9-41.9

170

136-204

Topiramate

3.04

2.43-3.65

21.4

17.1-25.7

Vigabatrin

5.35

4.28-6.42

30.7

24.6-36.8

N-Desmethylmesuximide

12.6

10.1-15.1

35.0

28-42

PEMA

2.09

1.67-2.51

8.28

6.62-9.94

Phenytoin

6.00

4.8-7.2

17.4

13.9-20.9

Primidone

5.19

4.15-6.23

14.1

11.3-16.9

Stiripentol

5.57

4.46-6.68

18.2

14.6-21.8

Ethosuximide

33.2

26.6-39.8

81.6

65.3-97.9

Phenobarbital

12.0

9.6-14.4

40.5

32.4-48.6

Valproic acid

43.3

34.6-52

87.7

70.2-105

Zonisamide

8.53

6.82-10.2

36.9

29.5-44.3

Brivaracetam

0.973

0.778-1.17

3.80

3.04-4.56

Perampanel (in µg/l)

175

140-210

1213

970-1456

Retigabine (in µg/l)

243

194-292

1786

1429-2143

Method of Analysis LC-MS/MS
Parameters 10,11-Dihydroxycarbamazepine, 10-OH-Carbamazepine, Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam (Keppra®), N-Desmethylmesuximide, Oxcarbamazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Pregabalin, Primidone, Retigabine, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic Acid, Zonisamide

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.

Brivaracetam

Carbamazepine

Carbamazepine-10,11-epoxide

10,11-Dihydroxycarbamazepine

10-OH-Carbamazepine

Oxcarbamazepine

Ethosuximide

Felbamate

Gabapentin

Lacosamide

Lamotrigine

Levetiracetam (Keppra®)

N-Desmethylmesuximide

Perampanel

Phenobarbital

Phenylethylmalonamide (PEMA)

Phenytoin

Pregabalin

Primidone

Retigabine

Rufinamide

Stiripentol

Sultiame

Theophylline

Tiagabine

Topiramate

Valproic acid

Vigabatrin

Zonisamide

MassCheck® Antiepileptic Drugs/EXTENDED Plasma Controls

For MassTox® TDM Series A Parameter Sets by LC-MS/MS:
Antiepileptic Drugs in Serum/Plasma (92921)
Antiepileptic Drugs All-in-One-Methode in Serum/Plasma (92921/XT)

0249/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0250/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level I (lyoph.), 5 x 1 ml
0251/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures in clinical diagnostics for the quantitative determination of antiepileptic drugs in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

More Information
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

NEW: An Excel file with the data from the product information leaflet is now available in the "Downloads" section (for registered customers only). This eliminates manual data entry of large data sets.

Substance

Target value

Level I

Target range

Level I

Target value

Level II

Target range

Level II

10-OH-Carbamazepine

7.80

6.24-9.36

33.9

27.1-40.7

Carbamazepine

3.17

2.54-3.8

10.6

8.48-12.7

Carbamazepine-10.11-epoxide

1.14

0.912-1.37

7.68

6.14-9.22

Carbamazepine-Diol

0.978

0.782-1.17

8.34

6.67-10

Oxcarbazepine

0.402

0.322-0.482

2.81

2.25-3.37

Felbamate

25.1

20.1-30.1

89.3

71.4-107

Lacosamide

1.84

1.47-2.21

8.28

6.62-9.94

Lamotrigine

3.21

2.57-3.85

12.7

10.2-15.2

Levetiracetam

16.6

13.3-19.9

68.3

54.6-82

Rufinamide

7.83

6.26-9.4

25.8

20.6-31

Theophylline

9.38

7.5-11.3

18.8

15-22.6

Gabapentin

4.13

3.3-4.96

19.4

15.5-23.3

Pregabalin

1.15

0.92-1.38

8.91

7.13-10.7

Sultiame

1.71

1.37-2.05

11.1

8.88-13.3

Tiagabine (in µg/l)

34.9

27.9-41.9

170

136-204

Topiramate

3.04

2.43-3.65

21.4

17.1-25.7

Vigabatrin

5.35

4.28-6.42

30.7

24.6-36.8

N-Desmethylmesuximide

12.6

10.1-15.1

35.0

28-42

PEMA

2.09

1.67-2.51

8.28

6.62-9.94

Phenytoin

6.00

4.8-7.2

17.4

13.9-20.9

Primidone

5.19

4.15-6.23

14.1

11.3-16.9

Stiripentol

5.57

4.46-6.68

18.2

14.6-21.8

Ethosuximide

33.2

26.6-39.8

81.6

65.3-97.9

Phenobarbital

12.0

9.6-14.4

40.5

32.4-48.6

Valproic acid

43.3

34.6-52

87.7

70.2-105

Zonisamide

8.53

6.82-10.2

36.9

29.5-44.3

Brivaracetam

0.973

0.778-1.17

3.80

3.04-4.56

Perampanel (in µg/l)

175

140-210

1213

970-1456

Retigabine (in µg/l)

243

194-292

1786

1429-2143

Method of Analysis LC-MS/MS
Parameters 10,11-Dihydroxycarbamazepine, 10-OH-Carbamazepine, Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam (Keppra®), N-Desmethylmesuximide, Oxcarbamazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Pregabalin, Primidone, Retigabine, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic Acid, Zonisamide

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.