NEW: Antiepileptic Drugs Parameter Set for MassTox® TDM Series A

MassTox® TDM Series A Parameter Set Antiepileptic Drugs XT2

All-in-One Method in Serum/Plasma

We’re proud to introduce the latest advancement in therapeutic drug monitoring: the MassTox® TDM Series A Parameter Set Antiepileptic Drugs XT2. This enhanced LC-MS/MS solution is designed to meet today’s clinical and regulatory demands.

The XT2 parameter set enables the rapid quantitative determination of 28 analytes in human serum or plasma. Medically indicated for patients receiving one or more antiepileptic drugs and/or theophylline, it delivers reliable results for therapeutic drug monitoring.

Parameter menu

Brivaracetam
Carbamazepine
Carbamazepine -10,11-epoxide
10 - OH - Carbamazepine
Cenobamate
N-Desmethylmesuximide
Ethosuximide
Felbamate

Gabapentin
Lacosamide
Lamotrigine
Levetiracetam
Oxcarbamazepine
Perampanel
Phenobarbital
Phenylethylmalonamide (PEMA)

Phenytoin
Pregabalin
Primidone
Rufinamide
Stiripentol
Sultiame

Tiagabine
Theophylline
Topiramate
Valproic acid
Vigabatrin
Zonisamide


What's new?

Expanded clinical coverage
Now includes cenobamate, a newly approved antiepileptic drug with growing therapeutic relevance.

One-to-one internal standards
Each analyte is paired with its own internal standard – enhancing accuracy and reproducibility.

Full IVDR certification
XT2 is now fully compliant with IVDR regulations, aligning with the latest European regulatory requirements.

Updated theophylline calibration
The Plasma Calibrator Level 3 has been adjusted to reflect new therapeutic reference ranges.

Trusted benefits maintained

All 28 analytes in a single run
A single chromatographic run delivers complete results – optimising turnaround time and lab efficiency.

No changes in the chromatography
The upgraded panel integrates seamlessly – no adjustments to gradient or run time are necessary.

Fully integrated with the MassTox® TDM Series A portfolio
Experience reliable and consistent performance with effortless implementation into your existing workflow.

Chromatogram

Take the next step and contact our expert team:

  • Schedule a personalised consultation tailored to your lab’s needs
  • Place an order or discuss volume pricing and availability
  • Learn how the XT2 parameter set can be integrated into your current MassTox® TDM Series A workflow

Don’t miss the opportunity to upgrade your therapeutic drug monitoring capabilities with a fully IVDR-compliant and efficient solution.

Probenvorbereitung

Die einfache Probenvorbereitung ist für alle Parameter-Sets der MassTox TDM Serie A identisch:

Zugabe von 800 μl Internal Standard Mix zu 12 ml Precipitation Reagent (= Mixture A).

50 μl Probe/Kalibrator/MassCheck® ­Kontrolle in ein 1,5 ml Reaktionsgefäß geben.

25 μl Extraction Buffer zugeben, kurz mischen (Vortex) und 2 min inkubieren.

250 μl der Mixture A dazugeben, 30 s mischen (Vortex) und 5 min zentrifugieren.

Überstand mit Dilution Buffer verdünnen (je nach Geräteempfindlichkeit) und in das LC-MS/MS-System injizieren.


 

Brochure download

You need all the facts at a glance? Then you are welcome to download our brochure.
After you have filled out the following form, the respective link to download your document will be sent to the e-mail address provided.

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