MassTox® TDM Series A Parameter Set Antiepileptic Drugs XT2
All-in-One Method in Serum/Plasma
We’re proud to introduce the latest advancement in therapeutic drug monitoring: the MassTox® TDM Series A Parameter Set Antiepileptic Drugs XT2. This enhanced LC-MS/MS solution is designed to meet today’s clinical and regulatory demands.
The XT2 parameter set enables the rapid quantitative determination of 28 analytes in human serum or plasma. Medically indicated for patients receiving one or more antiepileptic drugs and/or theophylline, it delivers reliable results for therapeutic drug monitoring.
Parameter menu
Brivaracetam
Carbamazepine
Carbamazepine -10,11-epoxide
10 - OH - Carbamazepine
Cenobamate
N-Desmethylmesuximide
Ethosuximide
Felbamate
Gabapentin
Lacosamide
Lamotrigine
Levetiracetam
Oxcarbamazepine
Perampanel
Phenobarbital
Phenylethylmalonamide (PEMA)
Phenytoin
Pregabalin
Primidone
Rufinamide
Stiripentol
Sultiame
Tiagabine
Theophylline
Topiramate
Valproic acid
Vigabatrin
Zonisamide
What's new?
Expanded clinical coverage
Now includes cenobamate, a newly approved antiepileptic drug with growing therapeutic relevance.
One-to-one internal standards
Each analyte is paired with its own internal standard – enhancing accuracy and reproducibility.
Full IVDR certification
XT2 is now fully compliant with IVDR regulations, aligning with the latest European regulatory requirements.
Updated theophylline calibration
The Plasma Calibrator Level 3 has been adjusted to reflect new therapeutic reference ranges.
Trusted benefits maintained
All 28 analytes in a single run
A single chromatographic run delivers complete results – optimising turnaround time and lab efficiency.
No changes in the chromatography
The upgraded panel integrates seamlessly – no adjustments to gradient or run time are necessary.
Fully integrated with the MassTox® TDM Series A portfolio
Experience reliable and consistent performance with effortless implementation into your existing workflow.
Chromatogram
Take the next step and contact our expert team:
- Schedule a personalised consultation tailored to your lab’s needs
- Place an order and discuss availability
- Learn how the XT2 parameter set can be integrated into your current MassTox® TDM Series A workflow
Don’t miss the opportunity to upgrade your therapeutic drug monitoring capabilities with a fully IVDR-compliant and efficient solution.
Probenvorbereitung
Die einfache Probenvorbereitung ist für alle Parameter-Sets der MassTox TDM Serie A identisch:
Zugabe von 800 μl Internal Standard Mix zu 12 ml Precipitation Reagent (= Mixture A).
50 μl Probe/Kalibrator/MassCheck® Kontrolle in ein 1,5 ml Reaktionsgefäß geben.
25 μl Extraction Buffer zugeben, kurz mischen (Vortex) und 2 min inkubieren.
250 μl der Mixture A dazugeben, 30 s mischen (Vortex) und 5 min zentrifugieren.
Überstand mit Dilution Buffer verdünnen (je nach Geräteempfindlichkeit) und in das LC-MS/MS-System injizieren.
Brochure download
