3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDED

Order No.: 92051/XT
Parameters:
5-Flucytosine, Anidulafungin, Caspofungin, Fluconazole, Hydroxyitraconazole, Isavuconazole, Itraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole
MassTox® TDM Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS

5-Flucytosine

Anidulafungin

Caspofungin

Fluconazole

Isavuconazole

Itraconazole

Hydroxyitraconazole

Ketoconazole

Micafungin

Posaconazole

Voriconazole

3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDED

For MassTox® TDM Series A Parameter Set Antimycotic Drugs/EXTENDED in Serum/Plasma by LC-MS/MS (92922/XT)

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of antimycotic drugs in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen. These calibrators are only available as multilevel calibrator set with 3 different concentration levels plus 1 blank value.

More Information
Content 4 x 1 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

 

NEW: An Excel file with the data from the product information leaflet is now available in the "Downloads" section (for registered customers only). This eliminates manual data entry of large data sets.

Substance  Calibrator 1
(mg/l)
Calibrator 2
(mg/l)
Calibrator 3
(mg/l)
Blank Calibrator
(mg/l)

Fluconazole

0.813

10.20

19.5

n.d.

5-Flucytosine

6.99

59.8

113

n.d.

Hydroxyitraconazole

0.224

1.32

2.48

n.d.

Itraconazole

0.191

1.10

2.01

n.d.

Ketoconazole

0.236

5.85

11.5

n.d.

Posaconazole

0.233

2.67

5.05

n.d.

Voriconazole

0.368

3.14

7.62

n.d.

Isavuconazole

0.519

9.47

20.50

n.d.

Anidulafungin

0.463

4.85

9.75

n.d.

Caspofungin

0.657

5.93

11.70

n.d.

Micafungin

2.120

25.90

66.10

n.d.

n.d. = not detected (< LOQ)

The blank level is manufactured using the same matrix pool as used for the calibrator levels 1, 2 and 3. It was not fortified with any antimycotic drug.

Method of Analysis LC-MS/MS
Parameters 5-Flucytosine, Anidulafungin, Caspofungin, Fluconazole, Hydroxyitraconazole, Isavuconazole, Itraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.

5-Flucytosine

Anidulafungin

Caspofungin

Fluconazole

Isavuconazole

Itraconazole

Hydroxyitraconazole

Ketoconazole

Micafungin

Posaconazole

Voriconazole

3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDED

For MassTox® TDM Series A Parameter Set Antimycotic Drugs/EXTENDED in Serum/Plasma by LC-MS/MS (92922/XT)

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of antimycotic drugs in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen. These calibrators are only available as multilevel calibrator set with 3 different concentration levels plus 1 blank value.

More Information
Content 4 x 1 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

 

NEW: An Excel file with the data from the product information leaflet is now available in the "Downloads" section (for registered customers only). This eliminates manual data entry of large data sets.

Substance  Calibrator 1
(mg/l)
Calibrator 2
(mg/l)
Calibrator 3
(mg/l)
Blank Calibrator
(mg/l)

Fluconazole

0.813

10.20

19.5

n.d.

5-Flucytosine

6.99

59.8

113

n.d.

Hydroxyitraconazole

0.224

1.32

2.48

n.d.

Itraconazole

0.191

1.10

2.01

n.d.

Ketoconazole

0.236

5.85

11.5

n.d.

Posaconazole

0.233

2.67

5.05

n.d.

Voriconazole

0.368

3.14

7.62

n.d.

Isavuconazole

0.519

9.47

20.50

n.d.

Anidulafungin

0.463

4.85

9.75

n.d.

Caspofungin

0.657

5.93

11.70

n.d.

Micafungin

2.120

25.90

66.10

n.d.

n.d. = not detected (< LOQ)

The blank level is manufactured using the same matrix pool as used for the calibrator levels 1, 2 and 3. It was not fortified with any antimycotic drug.

Method of Analysis LC-MS/MS
Parameters 5-Flucytosine, Anidulafungin, Caspofungin, Fluconazole, Hydroxyitraconazole, Isavuconazole, Itraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole

Download of Product Information Leaflets
For logged-in customers the product information leaflets for calibrators, controls, internal standards and tuning mixes can be downloaded from the downloadcenter.


Download of all other documents
In the below section logged-in customers can download various documents such as instruction manuals, safety data sheets, traceability chains for calibrators, and external quality assessments.
These documents can also be downloaded from the downloadcenter.

As a customer please login or register to gain full access.