Metabonomic profiling of neuroendocrine neoplasms has diagnostic potential according to this study and could be used for discovering biomarkers for these tumours. Authors conclude that preliminary data require confirmation in a larger cohort. 5-HIAA was measured with the Chromsystems HPLC assay
The study results point towards a catecholamine deficit in the peripheral nervous system in line with catecholamone deficit of the central nervous system and exhaustion in depression. Catecholamines measured with HPLC assay from Chromsystems.
Auricular vagus nerve stimulation with a Nemos device had no major acute effects on the autonomic regulation of peripheral organs and did therefore neither alter insulin sensitivity, insulin secretion, resting energy expenditure nor sympathovagal balance. Catecholamines were analysed with high performance liquid chromatography (HPLC) using the Chromsystems assay.
The study showed that dynamic and static strength exercise protocols using resistance bands both could provoke acute and chronic hormonal responses in boxers similar to more traditional modes of such exercise. Adrenaline and noradrenaline measured with the Chromsystems HPLC assay.
Auricular vagus nerve stimulation with the Nemos device had no major acute effects on the autonomic regulation of peripheral organs and did therefore neither alter insulin sensitivity, insulin secretion, resting energy expenditure nor sympathovagal balance. Catecholamines were measured with a Chromsystems HPLC assay.
The research shows that dynamic and static strength exercise protocols using resistance bands both could provoke acute and chronic hormonal responses in boxers similar to more traditional modes of such exercise. Plasma adrenaline and noradrenaline measured with Chromsystems HPLC assay.
In this study, we showed for the first time that noradrenaline in plasma was correlated with Mini Mental State Examination (MMSE) score in the context of Alzheimers. Noradrenalin was measured with the catecholamine assay from Chromsystems.
the population of young and healthy obese individuals in this study did not exhibit an increased behavioral sensitivity to cytokines, but an attenuated cortisol response to the immune challenge. Noradrenaline was measured with Chromsystems assay.
Our study reveals signs of inflammation, neuronal damage and transitory disruption of BBB following single GCS, underscoring the widespread and possibily detrimental effects of recurrent seizures on brain properties. The long term impact on the disease course, however, is unclear. Noradrenalin measured by HPLC with Chromsystems
Catecholamines were associated with stress and IQ, which suggests that the autonomic functional regulation of catecholamine levels in relation to stress may also affect cognitive functions related to intelligence in the brain. Study was conducted with HPLC assay from Chromsystems.
HTxRs are characterized by elevated blood pressures and total peripheral resistance at supine rest as well as attenuated blood pressures and total peripheral resistance responses during orthostatic challenge, possibly caused by low-pressure cardiopulmonary baroreceptor denervation. Noradrenaline and adrenaline were measured by the HPLC assay from Chromsystems
adrenal incidentaloma presented high frequency of metabolic syndrome. Possible deleterious effects of cortisol secretion seem to initially affect the muscular system, according to the paper that used the Chromsystems assay to determine pheochomocytoma.
Considering previous studies in this field, major depression may be related to impaired glucose/insulin homeostasis in the long-term but not in early disease stages. Catecholamines and metanephrines measured with Chromsystems HPLC assays.
Stated sex differences were shown to be independent of enhanced psychological stress and seem to be related to the environmental conditions. However, sources and consequences of these sex differences have to be further elucidated.. catecholamine concentrations was executed at the Institute of Clinical Chemistry, University of Munich, Munich, Germany, using HPLC (Chromsystems, Martinsried, Germany).
Our findings enhance our understanding of the ability of organisms to cope with unfavorable environments and illuminate some of the relevant signaling pathways.. Dopamine measured by HPLC with Chromsystems assay
The authors found consistent associations between altered markers of dopamine transmission and several objective and subjective mental impairments in healthy volunteers after 1 week's treatment with antidopaminergic medications. Catecholamines measured with Chromsystems HPLC assay.
The results imply that delay discounting is not susceptible to fluctuations of blood glucose and do not support the assumption that a low body’s energy content leads to increased impulsivity. Adrenaline and noradrenaline were measured by HPLC with the Chromsystems assay
adrenaline and noradrenaline were measured by the HPLC assay from Chromsystems
metabolomic and lipidomic strategies suggested potential early biomarkers in obstructive sleep apnoea that could also be helpful in screening for this sleep disorder beyond traditional questionnaires. Catehcolamines measured with Chromsystems assay.
The patients did not benefit from an extra dose of hydrocortisone in short strenuous exercise. Stress dosing may not be justified in this setting. Whether stress dosing is beneficial in other types of physical activity will have to be examined further.Noradrenalin and adrenalin was measured by HPLC
β2AR activity was a required substrate for α2AR auto inhibition of norepinephrine release in WKY. β1+2AR opposed α2AR inhibition of norepinephrine release in SHR and epinephrine secretion in both strains. βAR-α2AR reciprocal control of vascular tension was absent in SHR. Selective agonist provoked β3AR-Gi signaling and influenced the tyramine-induced TPR-response in WKY and catecholamine release in SHR. Catecholamines measured with Chromsystems HPLC assay.
Strong 123I-MIBG uptake and high serum level of neuron specfiic enolase (EN) were each predictive of unfavorable histopathology (H). Combined analysis of both parameters improved the prediction of UH in patients with neuroblastic tumor. MRI parameters and urine catecholamine levels did not predict UH.catecholamines, metanephrines, VMA, HVA, 5-HIAA all measured with Chromsystems HPLC assays.
esults support that increased IAH leads to discharge of catecholamine and corticosterone from the adrenal glands. Failure to demonstrate similar changes in apoptotic index score may be concluded as apoptosis is not a leading pathway for impairment of adrenal glands during IAH period. Adrenaline and noradrenaline measured with Chromsystems HPLCassay.
Low-dose clonidine reduces catecholamine levels in adolescent Chronic Fatigue Syndrome but the effects on autonomic cardiovascular control are sparse. Clonidine does not improve symptoms of orthostatic intolerance. Catecholamines measured with Chromsystems HPLC assay
These data suggest that in response to acute psychological stress both plasma noradrenaline levels and salivary alpha-amylase Activity reflect sympathetic activity, however seemed to increase independently from each other. Noradrenaline measured with Chromsystems HPLC assay.
the data indicate that there are important implications for the appropriate exercise intensity prescription in training programs designed to optimize fat oxidation in obese people. Noradrenaline and adrenaline were measured with Chromsystems HPLC assay
hese data argue for an imbalance between the hypothalamus-pituitary-adrenal axis and the vagal tone in Crohn's disease (CD) and irritable bowel syndrome (IBS). Noradrenlaine and adrenaline measured with Chromsystems HPLC assay.
Findings show that cardiac dysfunction seen early after subarachnoid hemorrhage was associated with both a rapid and sustained endogenous catecholamine release and WFNS score. SAH-induced cardiac dysfunction was regressive over the first week and paralleled the normalization of catecholamine concentration. Noradrenaline and adrenaline measured with HPLC assay from Chromsystems
The therapeutic features of a chelation modality established in translational models and in pilot clinical trials warrant comprehensive evaluation of symptomatic and/or disease-modifying potential of chelation in Parkinson's disease. Dopamine and metabolites measured with Chromsystems HPLC assay.
Findings indicate indeed opposing roles of mineralocorticoid (MR) and glucocorticoid receptor (GR) in memory retrieval, with optimal retrieval at intermediate cortisol levels likely mediated by high MR but concurrently low GR activation. Noradrenaline and adrenaline measured with Chromsystems assay.
In diabetics, particulate debris and coronary aspirate plasma contained more TNFα, which might reflect the activity of the underlying atherosclerotic process. Noradrenaline and adrenaline with Chromsystems HPLC assay measured.
ntermittent LS treatments decreased effectively and repetitively plasma vasoactive peptide levels, but no carryover effects were observed. Patients' symptoms decreased for the whole study period although there was no objective improvement of their exercise capacity. The prognostic significance of these effects needs to be further studied. epineprhine and norepinephrine measured by HPLC.
results suggest that partial adenosine A(1)-agonism dampens stress-induced tachycardia selectively in rats susceptible to strong increases in sympathetic activity, most likely due to a presynaptic attenuation of neurotransmitter norepinephrine release. Adrenaline and noradrenaline measured with Chromsystems assay.
The authors conclude that the brain under stressful conditions demands for energy from the body by using a mechanism, which we refer to as "cerebral insulin suppression" and in so doing it can satisfy its excessive needs. Noradrenaline and adrenaline were measured with Chromsystems HPLC assay.
Medium chain acylcarnitines were identified and characterized by a functional metabolomics approach as the dominating biomarkers during a moderately intense exercise bout possessing the power to support fat oxidation. Adrenaline and noradrenaline measured with Chromsystems assay.
Indomethacin, diclofenac, meloxicam and nimesulide were found to exert anti-inflammatory effects by decreasing adrenaline levels but not affecting corticosterone levels. The anti-inflammatory effects of the tested drugs was eliminated on rainy days due to the low level of corticosterone. Catecholamines were measured in serum/plasma with Chromsystems HPLC assay.
In conclusion, E/NE concentrations were higher after the morning meal, while AG showed an opposite behavior. These data, although requiring confirmation in larger samples, suggest an adjunctive possible mechanism explaining the unfavorable effects of evening eating on metabolic risk. NE and E measured with our HPLC assay.
Please find here publications as guides for reference ranges or therapeutic ranges. As they may differ from other published data. Data vary depending on patient population and measurement method, please determine ranges for your laboratory. When determining ranges make sure that you comply with local national requirements.
Gressner A.M., Arndt T. (Eds). Lexikon der Medizinischen Laboratoriumsdiagnostik, 3rd edition, Springer Verlag (2019).
These data establish that although levodopa treatment confounds identification of PPGLs that produce dopamine, the therapy is not a problem for use of LC-MS/MS measurements of plasma and urinary normetanephrine and metanephrine to diagnose more commonly encountered PPGLs that produce noradrenaline or adrenaline.
The distinct patterns of plasma catecholamine O-methylated metabolites in patients with hereditary pheochromocytoma provide an easily used tool to guide cost-effective genotyping of underlying disease-causing mutations.
Dietary restrictions should be considered to minimize false-positive results for urinary and plasma deconjugated MNs during diagnosis of pheochromocytoma. Similar considerations appear warranted for plasma and urinary free 3-MT, but not for free NMN or MN, indicating advantages of measurements of the free compared to deconjugated metabolites.