Sample Prep Set Total Metanephrines (free + conjugated) with 96 SPE Well Plate
Isotopically labelled internal standard for each analyte
6PLUS1® Multilevel Calibrator Set and MassCheck® controls
Fully automated workflow solution available
In addition to a Sample Prep Set the products of the Chromatographic Platform are required.


3-Methoxytyramine
Metanephrine
Normetanephrine
MassChrom® Biogenic Amines/Metabolites in Urine – LC-MS/MS
With 96 SPE well plate for 96 analyses (80600/96), suitable for manual and automated sample prep procedure
Clinical relevance
This Sample Prep Set allows the quantitative determination of total metanephrine, normetanephrine and 3-methoxytyramine in patient urine samples by LC-MS/MS.
One typical application for this kit is the analysis of patient samples with a suspicion of catecholamine-secreting tumours.
Product advantages
- Isotopically labelled internal standard for each analyte
- 6PLUS1® Multilevel Calibrator Set and MassCheck® controls ensure high precision of results
- Fully automated workflow solution available
This Sample Prep Set encompasses all required components for an efficient and fast sample preparation.
A fully automated workflow solution is also available.
Alternatively, there is also a method available using Sample Clean Up Columns (80700/C).
Method of Analysis | LC-MS/MS |
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Number of Tests | 96 |
Linearity | Metanephrine, Normetanephrine up to 20 mg/l |
Recovery | 92–107 % |
Intraassay | CV = 2.5–5.6 % |
Interassay | CV = 3.2–4.9 % |
Analysis Time | 4 min |
Specimen | 24h urine or spontaneous urine |
Pre-analytic Treatment | 24 h urine is collected in a suitable container with 10 ml of 10–25 % HCl. |
Sample Preparation |
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Sample Stability | Samples are stable for at least 7 days at +2°C to +8°C in amber coloured vials. For longer storage periods keep samples frozen below -18°C. |
Injection Volume | ≤ 20 µl |
Ionisation | ESI positive |
MS/MS-Mode | MRM |
Please note | The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals. |
Parameter | 3-Methoxytyramine, Metanephrine, Normetanephrine |
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Pierceable adhesive seals for 96 Well PlatesOrder no.: 80059
MassChrom® Biogenic Amines/Metabolites in Urine - LC-MS/MS
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6PLUS1® Multilevel Urine Calibrator Set Total Metanephrines (free + conjugated)Order no.: 80739
MassChrom® Total Metanephrines in Urine - LC-MS/MS
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MassCheck® Total Metanephrines Urine ControlsOrder no.: 0376/0377
MassChrom® Total Metanephrines in Urine - LC-MS/MS
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