Parameter Set Antimycotic Drugs/EXTENDED - LC-MS/MS
Encompasses 11 analytes
3PLUS1® Multilevel Calibrator Set and MassCheck® controls
Part of the modular system MassTox® Series A
5-Flucytosine
Anidulafungin
Caspofungin
Fluconazole
Isavuconazole
Itraconazole
Hydroxyitraconazole
Ketoconazole
Micafungin
Posaconazole
Voriconazole
Clinical relevance
This parameter set allows the quantitative determination of anidulafungin, caspofungin, fluconazole, 5-flucytosine, isavuconazole, itraconazole, hydroxyitraconazole, ketoconazole, micafungin, posaconazole and voriconazole in human serum or plasma samples via liquid chromatography mass spectrometry (LC-MS/MS).
MassTox® Series A
The MassTox® Series A is a modular system that enables the determination of all analytes without changing column or mobile phases, thereby minimising the workload in the laboratory.
It consists of 3 parts:
• MassTox® Basic Kit A
• Specific MassTox® Parameter Set
• Analytical column MassTox® TDM MasterColumn® A
| Method of Analysis | LC-MS/MS |
|---|---|
| Please note | The information listed here, including the sample preparation, is not sufficient for using the product. Please read the information provided in the instruction manual. |
| Specimen | Serum/Plasma |
| Sample Preparation |
|
| Run Time | 3.2 min |
| Injection Volume | 0.5 to 50 µl (mass spectrometer dependent) |
| Flow Rate | 0.6 ml/min |
| Column Temperature | +20 to +25 °C |
| Gradient | binary |
| Ionisation | ESI positive and negative, polarity switch possible |
| MS/MS Mode | MRM |
| Parameters | 5-Flucytosine, Anidulafungin, Caspofungin, Fluconazole, Hydroxyitraconazole, Isavuconazole, Itraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole |
92922/XT MassTox® Parameter Set Antimycotic Drugs/EXTENDED
| Order No. | MassTox® Basic Kit A |
| 92111/200/RUO | Basic Kit A for 200 tests |
| 92111/1000/RUO | Basic Kit A for 1000 tests |
| Order No. | MassTox® Basic Kit A (Quantities in kit for 200 tests) |
| 92001/RUO | Mobile Phase 1, 1000 ml (1x) |
| 92002/RUO | Mobile Phase 2, 1000 ml (1x) |
| 92003/RUO | Precipitation Reagent, 50 ml (1x) |
| 92005/RUO | Extraction Buffer, 5 ml (1x) |
| 92007/RUO | Dilution Buffer 1, 50 ml (1x) |
| 92008/RUO | Dilution Buffer 2, 50 ml (1x) |
| 92009/RUO | Rinsing Solution, 1000 ml (1x) |
| 33006 | Reaction Vials, transparent, 1.5 ml, 100 pcs. (2x) |
| 92922/XT | MassTox® Parameter Set Antimycotic Drugs/EXTENDED components |
| 92051/XT | 3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDED (lyoph.), 4 x 1 ml |
| 0253/XT | MassCheck® Antimycotic Drugs/EXTENDED Plasma Control, Level I (lyoph.), 5 x 1 ml |
| 0254/XT | MassCheck® Antimycotic Drugs/EXTENDED Plasma Control, Level II (lyoph.), 5 x 1 ml |
| 92644/XT/RUO | Internal Standard Mix Antimycotic Drugs/EXTENDED, 1 x 3.8 ml (for 200 tests) |
| Order No. | Required components (not included in the kit or the parameter set) |
| 92110 | MassTox® TDM MasterColumn® A, equilibrated, with test chromatogram, 1 pc. |
| 92039/XT/RUO | Tuning Mix Antimycotic Drugs/EXTENDED (Analytes and Internal Standards), 1 ml |
| Order No. | General lab equipment (non-CE/IVD products) |
| 15010 | PEEK Prefilter Housing, 1 pc. |
| 15011 | PEEK-encased Prefilter, 2 µm, 5 pcs. |
| 15070 | Stainless Steel Prefilter Housing, 1 pc. |
| 15071 | Stainless Steel Prefilter, 0.5 μm, 5 pcs. |
| 33006 | Reaction Vials, transparent, 1.5 ml, 100 pcs. |
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3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDEDOrder no.: 92051/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS -
MassCheck® Antimycotic Drugs/EXTENDED Plasma ControlsOrder no.: 0252/XT; 0253/XT; 0254/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS -
Internal Standard Mix Antimycotic Drugs/EXTENDEDOrder no.: 92644/XT/RUOComponent of the Parameter Set Antimycotic Drugs/EXTENDED
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Tuning Mix Antimycotic Drugs/EXTENDEDOrder no.: 92039/XT/RUOTuning Mix for the Parameter Set Antimycotic Drugs/EXTENDED - LC-MS/MS
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Basic Kit A for 200 Tests - LC-MS/MSOrder no.: 92111/200/RUO
Part of the modular system MassTox® Series A
Provides all components required for sample prep and all mobile phases -
Basic Kit A for 1000 Tests - LC-MS/MSOrder no.: 92111/1000/RUO
Part of the modular system MassTox® Series A
Provides all components required for sample prep and all mobile phases
-
3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDEDOrder no.: 92051/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS
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MassCheck® Antimycotic Drugs/EXTENDED Plasma ControlsOrder no.: 0252/XT; 0253/XT; 0254/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS
5-Flucytosine
Anidulafungin
Caspofungin
Fluconazole
Isavuconazole
Itraconazole
Hydroxyitraconazole
Ketoconazole
Micafungin
Posaconazole
Voriconazole
Clinical relevance
This parameter set allows the quantitative determination of anidulafungin, caspofungin, fluconazole, 5-flucytosine, isavuconazole, itraconazole, hydroxyitraconazole, ketoconazole, micafungin, posaconazole and voriconazole in human serum or plasma samples via liquid chromatography mass spectrometry (LC-MS/MS).
MassTox® Series A
The MassTox® Series A is a modular system that enables the determination of all analytes without changing column or mobile phases, thereby minimising the workload in the laboratory.
It consists of 3 parts:
• MassTox® Basic Kit A
• Specific MassTox® Parameter Set
• Analytical column MassTox® TDM MasterColumn® A
| Method of Analysis | LC-MS/MS |
|---|---|
| Please note | The information listed here, including the sample preparation, is not sufficient for using the product. Please read the information provided in the instruction manual. |
| Specimen | Serum/Plasma |
| Sample Preparation |
|
| Run Time | 3.2 min |
| Injection Volume | 0.5 to 50 µl (mass spectrometer dependent) |
| Flow Rate | 0.6 ml/min |
| Column Temperature | +20 to +25 °C |
| Gradient | binary |
| Ionisation | ESI positive and negative, polarity switch possible |
| MS/MS Mode | MRM |
| Parameters | 5-Flucytosine, Anidulafungin, Caspofungin, Fluconazole, Hydroxyitraconazole, Isavuconazole, Itraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole |
92922/XT MassTox® Parameter Set Antimycotic Drugs/EXTENDED
| Order No. | MassTox® Basic Kit A |
| 92111/200/RUO | Basic Kit A for 200 tests |
| 92111/1000/RUO | Basic Kit A for 1000 tests |
| Order No. | MassTox® Basic Kit A (Quantities in kit for 200 tests) |
| 92001/RUO | Mobile Phase 1, 1000 ml (1x) |
| 92002/RUO | Mobile Phase 2, 1000 ml (1x) |
| 92003/RUO | Precipitation Reagent, 50 ml (1x) |
| 92005/RUO | Extraction Buffer, 5 ml (1x) |
| 92007/RUO | Dilution Buffer 1, 50 ml (1x) |
| 92008/RUO | Dilution Buffer 2, 50 ml (1x) |
| 92009/RUO | Rinsing Solution, 1000 ml (1x) |
| 33006 | Reaction Vials, transparent, 1.5 ml, 100 pcs. (2x) |
| 92922/XT | MassTox® Parameter Set Antimycotic Drugs/EXTENDED components |
| 92051/XT | 3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDED (lyoph.), 4 x 1 ml |
| 0253/XT | MassCheck® Antimycotic Drugs/EXTENDED Plasma Control, Level I (lyoph.), 5 x 1 ml |
| 0254/XT | MassCheck® Antimycotic Drugs/EXTENDED Plasma Control, Level II (lyoph.), 5 x 1 ml |
| 92644/XT/RUO | Internal Standard Mix Antimycotic Drugs/EXTENDED, 1 x 3.8 ml (for 200 tests) |
| Order No. | Required components (not included in the kit or the parameter set) |
| 92110 | MassTox® TDM MasterColumn® A, equilibrated, with test chromatogram, 1 pc. |
| 92039/XT/RUO | Tuning Mix Antimycotic Drugs/EXTENDED (Analytes and Internal Standards), 1 ml |
| Order No. | General lab equipment (non-CE/IVD products) |
| 15010 | PEEK Prefilter Housing, 1 pc. |
| 15011 | PEEK-encased Prefilter, 2 µm, 5 pcs. |
| 15070 | Stainless Steel Prefilter Housing, 1 pc. |
| 15071 | Stainless Steel Prefilter, 0.5 μm, 5 pcs. |
| 33006 | Reaction Vials, transparent, 1.5 ml, 100 pcs. |
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3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDEDOrder no.: 92051/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS
-
MassCheck® Antimycotic Drugs/EXTENDED Plasma ControlsOrder no.: 0252/XT; 0253/XT; 0254/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS
-
Internal Standard Mix Antimycotic Drugs/EXTENDEDOrder no.: 92644/XT/RUOComponent of the Parameter Set Antimycotic Drugs/EXTENDED
-
-
Tuning Mix Antimycotic Drugs/EXTENDEDOrder no.: 92039/XT/RUOTuning Mix for the Parameter Set Antimycotic Drugs/EXTENDED - LC-MS/MS
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Basic Kit A for 200 Tests - LC-MS/MSOrder no.: 92111/200/RUO
Part of the modular system MassTox® Series A
Provides all components required for sample prep and all mobile phases -
Basic Kit A for 1000 Tests - LC-MS/MSOrder no.: 92111/1000/RUO
Part of the modular system MassTox® Series A
Provides all components required for sample prep and all mobile phases
-
3PLUS1® Multilevel Plasma Calibrator Set Antimycotic Drugs/EXTENDEDOrder no.: 92051/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS
-
MassCheck® Antimycotic Drugs/EXTENDED Plasma ControlsOrder no.: 0252/XT; 0253/XT; 0254/XTMassTox® Series A Antimycotic Drugs/EXTENDED in Serum/Plasma – LC-MS/MS