Simvastatin therapy has beneficial effects on inflammatory markers in plasma, but CoQ10 supplementation seems to have no additional potentiating effect in patients in primary prevention. In contrast, glucose homeostasis may improve with CoQ10 supplementation. Q10 measured with Chromsystems assay.
The authors extend the phenotypic spectrum of a recently identified mutation in COX20 to a recessively inherited, early-onset dystonia-ataxia syndrome that is characterized by reduced complex IV activity. Further, they confirm a pathogenic role of this mutation in cerebellar ataxia, but this mutation seems to be a rather rare cause. Q10 measured with Chromsystems assay.
The findings that lower CoQ10 is a risk factor to coronary artery disease and chronic heart failure (CHF) and mortality due to CHF suggest that low CoQ10 is another factor explaining the risk to cardiovascular disorder in depression. Q10 was measured by Chromsystems assay.
We suggest to give patients both CoQ10 and riboflavin supplementation, especially for long-term treatment of Q10 deficiency. Q10 measured with Chromsystems assay.
Please find here publications as guides for reference ranges or therapeutic ranges. As they may differ from other published data. Data vary depending on patient population and measurement method, please determine ranges for your laboratory. When determining ranges make sure that you comply with local national requirements.