Parameter Set Antiepileptic Drugs - LC-MS/MS
Encompasses 26 analytes
3PLUS1® Multilevel Calibrator Set available
Part of the modular system MassTox® Series A










Carbamazepine
Carbamazepine-10,11-epoxide
10,11-Dihydroxycarbamazepine
10-OH-Carbamazepine
Oxcarbamazepine
Ethosuximide
Felbamate
Gabapentin
Lacosamide
Lamotrigine
Levetiracetam (Keppra®)
N-Desmethylmesuximide
Phenobarbital
Phenylethylmalonamide (PEMA)
Phenytoin
Pregabalin
Primidone
Rufinamide
Stiripentol
Sultiame
Theophyllie
Tiagabine
Topiramate
Valproic acid
Vigabatrin
Zonisamid
The modular system MassTox® Basic Kit A in combination with the MassTox® Parameter Set for Antiepileptic Drugs allows for the fast quantitative determination of 26 different analytes in serum/plasma by LC-MS/MS. The use of stable isotopically marked and co-eluating internal standards ensures high performance of the analysis method.
For the analysis you require the MassTox® Basic Kit A, the specifc MassTox® Parameter Set and the analytical column MassTox® MasterColumn® A.
Analysis Time | 2.5 – 3.5 min |
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Sample Preparation |
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Sample Stability | Stability of research samples depends on the specific analyte. Further information can be optained from the instruction manual. |
Specimen | Serum/Plasma |
Injection Volume | 0.2 – 50 µl |
Gradient | Starting point: 0% Mobile Phase 2 Group 1 Group 2 and 3 Group 4 and 5 |
Ionisation | ESI positive and negative |
MS/MS-Mode | MRM |
Additional Info | We recommend to set the scan time to a value that allows to achieve a minimum of 10 data points over the whole peak width. |
Please note | The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals. |
Method of Analysis | LC-MS/MS |
Parameter | 10-OH-Carbamazepine, Carbamazepine, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, N-Desmethylmesuximide, Phenobarbital, Phenytoin, Pregabalin, Primidone, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic Acid, Vigabatrin, Zonisamide |
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Internal Standard Mix Antiepileptic DrugsOrder no.: 92546/RUOComponent of the Parameter Set Antiepileptic Drugs, available separately
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Tuning Mix Antiepileptic Drugs/EXTENDED 1Order no.: 92034/XT/RUOTuning Mix 1 for the Parameter Set Antiepileptic Drugs - LC-MS/MS
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Tuning Mix Antiepileptic Drugs/EXTENDED 2Order no.: 92035/XT/RUOTuning Mix 2 for the Parameter Set Antiepileptic Drugs - LC-MS/MS
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Tuning Mix Antiepileptic Drugs/EXTENDED 3Order no.: 92036/XT/RUOTuning Mix 3 for the Parameter Set Antiepileptic Drugs - LC-MS/MS
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Tuning Mix Antiepileptic Drugs/EXTENDED 4Order no.: 92037/XT/RUOTuning Mix 4 for the Parameter Set Antiepileptic Drugs - LC-MS/MS
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Tuning Mix Antiepileptic Drugs/EXTENDED 5Order no.: 92038/XT/RUOTuning Mix 5 for the Parameter Set Antiepileptic Drugs - LC-MS/MS