3PLUS1® Multilevel Plasma Calibrator Set Neuroleptics 1/ EXTENDED

Order No.: 92028/XT
Parameters:
9-OH-Risperidone, Aripiprazole, Clozapine, Dehydroaripiprazole, Haloperidol, N-Desmethylclozapine, N-Desmethylolanzapine, Norquetiapine, Olanzapine, Quetiapine, Risperidone

Aripiprazole

Dehydroaripiprazole

Clozapine

N-Desmethylclozapine

Haloperidol

Olanzapine

N-Desmethylolanzapine

Quetiapine

Norquetiapine

Risperidone

9-OH-Risperidone

3PLUS1® Multilevel Calibrator Set Neuroleptics 1/EXTENDED, lyophilised
Related MassTox® Series A Parameter Set: Neuroleptics 1/EXTENDED in Serum/Plasma (92912/XT/RUO)

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to calibrate the measurement method  for the quantitative determination of neuroleptics 1/EXTENDED in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 3 different concentration levels plus 1 blank value.

More Information
Content 4 x 1 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance Calibrator 1
(µg/l)
Calibrator 2
(µg/l)
Calibrator 3
(µg/l)
Blank Calibrator
(µg/l)
Aripiprazole 10.5 193 660 n.d.
Dehydroaripiprazole 6.93 91.8 262 n.d.
Clozapine 75.6 444 1186 n.d.
N-Desmethylclozapine 70.7 192 444 n.d.
Haloperidol 1.99 15.9 30.7 n.d.
Olanzapine 3.96 48.7 143 n.d.
N-Desmethylolanzapine 4.06 50.2 159 n.d.
Quetiapine 7.60 188 565 n.d.
Norquetiapine 10.3 158 314 n.d.
Risperidone 1.85 11.6 29.6 n.d.
9-OH-Risperidone 4.45 58.3 168 n.d.

n.d. = not detected (< LOQ)

The blank level is manufactured using the same matrix pool as used for the calibrator levels 1, 2 and 3. It was not fortified with any neuroleptics.

Reconstitution

Carefully remove the rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised calibrators are stable until the expiry date specified on the vial labels. The reconstituted calibrators can be stored in glass containers up to 3 days light protected and tightly capped at +2 to +8 C. If the calibrators cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.

Method of Analysis LC-MS/MS
Parameter 9-OH-Risperidone, Aripiprazole, Clozapine, Dehydroaripiprazole, Haloperidol, N-Desmethylclozapine, N-Desmethylolanzapine, Norquetiapine, Olanzapine, Quetiapine, Risperidone
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