Basic Kit A for 200 Tests - LC-MS/MS

Order No.: 92111/200/RUO, for 200 tests
Parameters:
70 grouped in 5 sets

Part of the modular system MassTox® Series A
Provides all components required for sample prep and all mobile phases

Basic Kit for all Parameters of Series A

Antiepileptic Drugs (92921/RUO)

Carbamazepine, Carbamazepine-10,11-epoxide, 10-OH-Carbamazepine, 10,11-Dihydroxycarbamazepine, Desmethylmesuximide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam, Oxcarbazepine, Phenobarbital, Phenylethylmalonamide (PEMA), Phenytoin, Pregabalin, Primidone, Rufinamide, Stiripentol, Sultiame, Tiagabine, Theophylline, Topiramate, Valproic acid, Vigabatrin, Zonisamide

Anti-HIV Drugs (92924/RUO)

Amprenavir, Atazanavir, Darunavir, Delavirdine, Efavirenz, Elvitegravir, Etravirine, Indinavir, Lopinavir, Maraviroc, Nelfinavir, Nelfinavir-M8, Nevirapine, Raltegravir, Rilpivirine, Ritonavir, Saquinavir

Antimycotic Drugs/EXTENDED (92922/XT/RUO)

Amphotericin B, Anidulafungin, Caspofungin, Fluconazole, 5-Flucytosine, Isavuconazole, Itraconazole, Hydroxyitraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole

Mycophenolic Acid (92916/RUO)

Mycophenolic acid, Mycophenolic acid glucuronide

Neuroleptics 1/EXTENDED (92912/XT/RUO)

Aripiprazole, Dehydroaripiprazole, Clozapine, N-Desmethylclozapine, Haloperidol, Olanzapine, N-Desmethylolanzapine, Quetiapine, Norquetiapine, Risperidone, 9-OH-Risperidone

 

The Basic Kit allows the rapid quantitative determination of a multitude of substances in serum or plasma by LC-MS/MS. To perform the analysis, you will need the MassTox® Basic Kit A, the substance-specific MassTox® Parameter Set and the analytical column MassTox® TDM MasterColumn® A.

Preparation of the research samples is the same for all parameters, based on a simple, effective protein precipitation process. The use of stable isotope-labelled (deuterated) internal standards ensures high performance of the analysis.

The Basic Kit A is available for 200 and 1000 analyses.

Content:

1 x Mobile Phase 1 (92001/RUO)
1 x Mobile Phase 2 (92002/RUO)
1 x Precipitation Reagent (92003/RUO)
1 x Extraction Buffer (92005/RUO)
1 x Dilution Buffer 1 (92007/RUO)
1 x Dilution Buffer 2 (92008/RUO)
1 x Rinsing Solution (92009/RUO)
2 x Reaction vials (33006)

More Information
Method of Analysis LC-MS/MS
Number of Tests 200
Please note The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals.
Sample Preparation

The sample preparation is standard for all Series A analytes.

  • Add 800 µl Internal Standard mix to 12 ml Precipitation Reagent to form mixture A
  • Place 50 µl sample/calibrator/MassCheck® control into a 1.5 ml reaction vial
  • Add 25 µl Extraction Buffer
  • Mix and incubate 2 min at ambient temperature (do not centrifuge)
  • Add 250 µl of mixture A and mix 30 sec minimum (vortex)
  • Centrifuge 5 min at 9000 x g
  • Dilute the supernatant with Dilution Buffer prior to injection depending on instrument sensitivity
Parameters 70 grouped in 5 sets
The following components are included in the kit:

Basic Kit for all Parameters of Series A

Antiepileptic Drugs (92921/RUO)

Carbamazepine, Carbamazepine-10,11-epoxide, 10-OH-Carbamazepine, 10,11-Dihydroxycarbamazepine, Desmethylmesuximide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam, Oxcarbazepine, Phenobarbital, Phenylethylmalonamide (PEMA), Phenytoin, Pregabalin, Primidone, Rufinamide, Stiripentol, Sultiame, Tiagabine, Theophylline, Topiramate, Valproic acid, Vigabatrin, Zonisamide

Anti-HIV Drugs (92924/RUO)

Amprenavir, Atazanavir, Darunavir, Delavirdine, Efavirenz, Elvitegravir, Etravirine, Indinavir, Lopinavir, Maraviroc, Nelfinavir, Nelfinavir-M8, Nevirapine, Raltegravir, Rilpivirine, Ritonavir, Saquinavir

Antimycotic Drugs/EXTENDED (92922/XT/RUO)

Amphotericin B, Anidulafungin, Caspofungin, Fluconazole, 5-Flucytosine, Isavuconazole, Itraconazole, Hydroxyitraconazole, Ketoconazole, Micafungin, Posaconazole, Voriconazole

Mycophenolic Acid (92916/RUO)

Mycophenolic acid, Mycophenolic acid glucuronide

Neuroleptics 1/EXTENDED (92912/XT/RUO)

Aripiprazole, Dehydroaripiprazole, Clozapine, N-Desmethylclozapine, Haloperidol, Olanzapine, N-Desmethylolanzapine, Quetiapine, Norquetiapine, Risperidone, 9-OH-Risperidone

 

The Basic Kit allows the rapid quantitative determination of a multitude of substances in serum or plasma by LC-MS/MS. To perform the analysis, you will need the MassTox® Basic Kit A, the substance-specific MassTox® Parameter Set and the analytical column MassTox® TDM MasterColumn® A.

Preparation of the research samples is the same for all parameters, based on a simple, effective protein precipitation process. The use of stable isotope-labelled (deuterated) internal standards ensures high performance of the analysis.

The Basic Kit A is available for 200 and 1000 analyses.

Content:

1 x Mobile Phase 1 (92001/RUO)
1 x Mobile Phase 2 (92002/RUO)
1 x Precipitation Reagent (92003/RUO)
1 x Extraction Buffer (92005/RUO)
1 x Dilution Buffer 1 (92007/RUO)
1 x Dilution Buffer 2 (92008/RUO)
1 x Rinsing Solution (92009/RUO)
2 x Reaction vials (33006)

More Information
Method of Analysis LC-MS/MS
Number of Tests 200
Please note The freely available information on this website, in particular on the sample preparation, are not sufficient to work with our products. Please read instructions and warning notices on products and/or instruction manuals.
Sample Preparation

The sample preparation is standard for all Series A analytes.

  • Add 800 µl Internal Standard mix to 12 ml Precipitation Reagent to form mixture A
  • Place 50 µl sample/calibrator/MassCheck® control into a 1.5 ml reaction vial
  • Add 25 µl Extraction Buffer
  • Mix and incubate 2 min at ambient temperature (do not centrifuge)
  • Add 250 µl of mixture A and mix 30 sec minimum (vortex)
  • Centrifuge 5 min at 9000 x g
  • Dilute the supernatant with Dilution Buffer prior to injection depending on instrument sensitivity
Parameters 70 grouped in 5 sets
The following components are included in the kit: