3PLUS1® Multilevel Plasma Calibrator Set Neuroleptics 2/ EXTENDED 2

Order No.: 92026/XT2
Parameters:
Amisulpride, Benperidol, Brexpiprazole, Bromperidol, Cariprazine, Chlorpromazine, Chlorprothixene, Flupentixol, Fluphenazine, Guanfacine, Iloperidone, Levomepromazine, Loxapine, Lurasidone, Melperone, Perazine, Perphenazine, Pimozide, Pipamperone, Promethazine, Prothipendyl, Sertindole, Sulforidazine, Sulpiride, Thioridazine, Ziprasidone, Zotepine, Zuclopenthixol

Amisulpride

Benperidol

Brexpiprazole

Bromperidol

Cariprazine

Chlorpromazine

Chlorprothixene

Flupentixol

Fluphenazine

Guanfacine

 

Iloperidone

Levomepromazine

Loxapine

Lurasidone

Melperone

Perazine

Perphenazine

Pimozide

Pipamperone

Promethazine

 

Prothipendyl

Sertindole

Sulforidazine

Sulpiride

Thioridazine

Ziprasidone

Zotepine

Zuclopenthixol

3PLUS1® Multilevel Plasma Calibrator Set Neuroleptics 2/EXTENDED 2, lyophilised

These lyophilised calibrators from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to calibrate the measurement method in clinical diagnostics for the quantitative determination of neuroleptics 2/EXTENDED 2 in serum/plasma. While following the instructions the calibrators should be handled and measured in the same manner as a patient specimen.
These calibrators are only available as multilevel calibrator set with 3 different concentration levels plus 1 blank value.

More Information
Content 4 x 1 ml (lyoph.)
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance Calibrator 1
µg/l]
Calibrator 2
µg/l]
Calibrator 3
µg/l]
Blank Calibrator
Amisulpride 26,2 274 530 n.d. (<8.24)
Benperidol 1,1 7,11 13,9 n.d. (<0.302)
Brexpiprazole 28,4 81,6 138 n.d. (<5.46)
Bromperidol 2,04 12 26,4 n.d. (<1.25)
Cariprazine 8,21 16,3 23,4 n.d. (<2.76)
Chlorpromazine 23,8 291 574 n.d. (<4.83)
Chlorprothixene 14,6 197 384 n.d. (<4.85)
Flupentixol 1,06 9,25 17,6 n.d. (<0.305)
Fluphenazine 0,99 9,9 19,8 n.d. (<0.294)
Guanfacine 0,99 7,84 17,5 n.d. (<0.096)
Iloperidone 4,06 8,1 12,2 n.d. (<1.35)
Levomepromazine 3,56 102 205 n.d. (<0.704)
Loxapine 4,63 18,3 42,3 n.d. (<1.42)
Lurasidone 10,4 25,2 39,2 n.d. (<0.954)
Melperone 20,1 624 1250 n.d. (<5.25)
Perazine 14,5 260 509 n.d. (<4.16)
Perphenazine 0,61 17 36,42 n.d. (<0.299)
Pimozide 2,84 12,2 22,6 n.d. (<1.01)
Pipamperone 14,4 256 512 n.d. (<2.26)
Promethazine 13 212 426 n.d. (<1.04)
Protipendyl 4,06 109 220 n.d. (<1.20)
Sertindole 2,71 54,1 115 n.d. (<0.674)
Sulforidazine 36,2 515 930 n.d. (<11.5)
Sulpiride 29 614 1134 n.d. (<13.3)
Thioridazine 65 1193 2354 n.d. (<8.44)
Ziprasidone 13,8 125 238 n.d. (<2.16)
Zotepine 7,54 99,2 191 n.d. (<0.937)
Zuclopenthixol 2,76 60,5 120,4 n.d. (<0.915)

n.d. = not detected (< LOQ)

The blank level is manufactured using the same matrix pool as used for the calibrator levels 1, 2 and 3. It was not fortified with any neuroleptics.

Reconstitution

Carefully remove the rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised calibrators are stable until the expiry date specified on the vial labels. The reconstituted calibrators can be stored in glass containers up to 1 week light protected and tightly capped at +2 to +8 C. If the calibrators cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.

Method of Analysis LC-MS/MS
Parameter Amisulpride, Benperidol, Brexpiprazole, Bromperidol, Cariprazine, Chlorpromazine, Chlorprothixene, Flupentixol, Fluphenazine, Guanfacine, Iloperidone, Levomepromazine, Loxapine, Lurasidone, Melperone, Perazine, Perphenazine, Pimozide, Pipamperone, Promethazine, Prothipendyl, Sertindole, Sulforidazine, Sulpiride, Thioridazine, Ziprasidone, Zotepine, Zuclopenthixol
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