This study shows that nearly one in four of the GP-tested population in Dublin and surrounding areas are vitamin D deficient in the winter, during which time up to 50% have 25(OH)D less than 50 nmol/L. Measured with MassChrom Vitamin D assay.
The highest prevalence of inadequacy of serum concentrations of 25(OH)D and greater severity of this deficiency in individuals with MUHO phenotype were observed. Vitamin D was measured by the Chromsystems HPLC assay.
This study concludes that given the importance of vitamin D for health, a sub-population could be at a significantly increased risk of rickets, impaired bone metabolism, and osteoporosis. MassChrom Vitamin D assay was used for the determination of vitamin D.
According to this study, monitoring the nutritional status of vitamin D in individuals with obesity that present with metabolically unhealthy obesity phenotype may contribute to minimize the occurrence and aggravation of diseases associated with obesity.
A high phosphorus intake strongly affected the formation of vascular lesions, cardiac morphology, and lipid metabolism, although these changes are not indicative of an increased cardiovascular risk. MassChrom Vitamin D assay was used.
On the basis of this preliminary observation, vitamin D supplementation might be a useful measure to reduce the risk of infection. Vitamin D was measured with MassChrom assay combined with MassSTAR automation platform.
understanding the local vitamin D system in skeletal muscle could help develop effective interventions for vitamin D supplementation to improve skeletal muscle mass and function during ageing. massChrom Vitamin D measured Vitamin D.
The authors suggest that sunshine is an important determinant of 25(OH )D concentration, even in those who are taking high‐dose vitamin D supplements and reside at a higher mid‐latitude location. Vitamin D concentrations were measured with the MassChrom Vitamin D assay.
These findings suggest that vitamin D at moderate levels may exert a direct regulatory effect, while continuous high dose vitamin D treatment could trigger multiple sclerosis disease activity by raising mean levels of T-cell excitatory calcium. Measured with massChrom Vitamin D assay.
This study showed for the first time that patients from LMIC who presented to ED with UAP displayed VDD. Validation from larger studies is warranted to evaluate the linkage of VDD with UAP. Measured with MassChrom Vitamin D assay.
Vitamin D supplement intake during pregnancy was found to be the most actionable determinant of vitamin D status, suggesting that vitamin D supplementation during pregnancy should receive more attention in clinical practice. MassChrom Vitamin D was used in combination with MassSTAR, an automated solution.
HIV-infected children have compromised bone mass and the presence of puberty seems to provide suitability of these parameters. The vitmin D levels were anylsed by using the HPLC assay from Chromsystems.
The interaction between vitamin D status, as measured by circulating 25(OH)D and DBP rs2282679 genotypes, modified the association between 25(OH)D and BMD and bone markers. Differences in DBP genotypes additionally influenced the correlation of fetuin-A levels with femoral BMD. Measured with the Chromsystems LC-MS/MS assay.
data suggest that presurgery vitamin D levels influence the size of genotype effects of FTO rs9939609 on RYGB surgery-induced weight loss in obese patients. HPLC- Vitamin D Assay from Chromsystems was used
The researchers' obersavations suggest a detrimental role of vitamin D deficiency in bacterial central nervous system infections. Vitamin D that was measured with the MassChrom assay may exert immune regulatory functions.
Low bone mineral density in young individuals was associated with greater gingival inflammation and recession when compared to those individuals with normal BMD values. Measured with HPLC Vitamin D assay.
Data reveal that the cholesterol-lowering effect of lupin protein isolate is attributable to an increased faecal output of cholesterol and a reduced intestinal uptake of cholesterol. Vitamin D in this study was measured by MassChrom Vitamin D.
in order to avoid vitamin D deficiency and rickets, the authors recommend supplementation dose of vitamin D at 400 IU/day as a safe and effective dose. Chromsystems HPLC assay was usd for the dtermination of vitamin D.
Data confirm previous reports on high prevalences of nutritional deficiencies in severely obese subjects. However, they do not provide evidence for a contributing role of gastric H. pylori infection to these nutritional alterations. HPLC assay from Chromsystems was used to determine Vitamin D.
The study concludes that some women who are vitamin D insufficient develop secondary hyperparathyroidism, which is associated with increased risk of preeclampsia. Vitamin D measured by Chromsystems HPLC assay.
The results in the paper suggest that the serum level of 25-hydroxyvitamin D is not crucially involved in the correlation between vitamin D status and T cell regulation in cord blood. Measured by Chromsystems HPLC assay
Patients with NPHPT do not exhibit insulin resistance and glucose intolerance. Since so little is known about this form of disease, subjects should be monitored regularly for the metabolic aspects of the disease as well as the progression of their disease. vitsamin D measured by HPLC with Chromsystems assay.
Cytosolic malic enzyme 1 gene polymorphism is associated with the degree of suppression of parathyroid hormone after long-term calcium supplementation. The effect is probably mediated through an increase in intestinal calcium absorption. Vitamin D was anylsed by the MassChrom Vitamin D assay.
After surgery, patients with low eGFR had preserved renal function, whereas those with normal eGFR had decreased renal function. Mild renal dysfunction in PHPT was associated with older age, hypertension, and high calcium levels.
the first study to demonstrate genetic models concerning the variation in C3-epimer levels. Their results emphasize that genetic determinants and the potential factors of C3-epimers differ from non-C3-epimers. Vitamin D was measured by MassChrom assay.
Vitamin D supplement intake was the most actionable determinant of vitamin D status, suggesting that vitamin D supplementation during pregnancy should receive more attention in clinical practice. Vitamin D measured with MassChrom Vitamin D assay on a MassSTAR instrument.
A high percentage of Thai adults had detectable 3-epi-25(OH)D3 that was <10 % of the total 25(OH)D levels. Age, gender, and living in a rural area were associated with the relative amount of 3-epi-25(OH)D3 to total 25(OH)D3. Measured with the MassChrom Vitamin D assay with the epimer upgrade.
The gel Saerum Separator Tubes do not interfere with the measurement of 25OHD3 by HPLC or common immunoassays. This important finding may enable clinical laboratories to make cost savings by using SSTs without concerns about inaccuracy.
Our results demonstrate considerable differences in the measurement of 25-hydroxyvitamin D concentrations compared with a certified laboratory, even between laboratories using assays based on liquid chromatography-tandem mass spectrometry, which is often considered the gold-standard assay.
The authors note that the vast majority of commercial laboratories rely on automated immunoassays, many of which are known to read low compared with LC-MS/MS. all laboratories should monitor their performance with an accuracy-based quality assurance system, with regular checks, and should, ideally, comply with international standardisation efforts.
Please find here publications as guides for reference ranges or therapeutic ranges. As they may differ from other published data. Data vary depending on patient population and measurement method, please determine ranges for your laboratory. When determining ranges make sure that you comply with local national requirements.
Thomas L. (ed)- Labor und Diagnose, 8th edition, TH books (2012)