MassCheck® Antiepileptic Drugs/EXTENDED Plasma Controls

Order No.: 0249/XT;0250/XT;0251/XT
Parameters:
10,11-Dihydroxycarbamazepine, 10-OH-Carbamazepine, Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam (Keppra®), N-Desmethylmesuximide, Oxcarbamazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Pregabalin, Primidone, Retigabine, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic Acid, Zonisamide
Grouped product items
Product Name Qty
MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Bi-Level (I+II)
Order No.: 0249/XT
MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level I
Order No.: 0250/XT
MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level II
Order No.: 0251/XT

Brivaracetam

Carbamazepine

Carbamazepine-10,11-epoxide

10,11-Dihydroxycarbamazepine

10-OH-Carbamazepine

Oxcarbamazepine

Ethosuximide

Felbamate

Gabapentin

Lacosamide

Lamotrigine

Levetiracetam (Keppra®)

N-Desmethylmesuximide

Perampanel

Phenobarbital

Phenylethylmalonamide (PEMA)

Phenytoin

Pregabalin

Primidone

Retigabine

Rufinamide

Stiripentol

Sultiame

Theophylline

Tiagabine

Topiramate

Valproic acid

Vigabatrin

Zonisamide

MassCheck® Antiepileptic Drugs/EXTENDED Plasma Controls, lyophilised
Related MassTox® Series A Parameter Set: Antiepileptic Drugs in Serum/Plasma (92921/RUO)

0249/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Bi-Level I + II (lyoph.), 2 x 5 x 1 ml
0250/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level I (lyoph.), 5 x 1 ml
0251/XT MassCheck® Antiepileptic Drugs/EXTENDED Plasma Control, Level II (lyoph.), 5 x 1 ml

These lyophilised quality controls from Chromsystems are based on human plasma and should be used according to the instruction manual. They are designed to monitor the accuracy and precision of analytical procedures for the quantitative determination of antiepileptic drugs in serum/plasma. While following the instructions the controls should be handled and measured in the same manner as a patient specimen.

More Information
Concentrations

Please note: Concentration values shown here are typical. For lot specific concentration values please refer to the product insert supplied with the materials. The product inserts can also be requested from us directly or downloaded from our website after login.

Substance

Target value

Level I

Target range

Level I

Target value

Level II

Target range

Level II

10-OH-Carbamazepine

7.80

6.24-9.36

33.9

27.1-40.7

Carbamazepine

3.17

2.54-3.8

10.6

8.48-12.7

Carbamazepine-10.11-epoxide

1.14

0.912-1.37

7.68

6.14-9.22

Carbamazepine-Diol

0.978

0.782-1.17

8.34

6.67-10

Oxcarbazepine

0.402

0.322-0.482

2.81

2.25-3.37

Felbamate

25.1

20.1-30.1

89.3

71.4-107

Lacosamide

1.84

1.47-2.21

8.28

6.62-9.94

Lamotrigine

3.21

2.57-3.85

12.7

10.2-15.2

Levetiracetam

16.6

13.3-19.9

68.3

54.6-82

Rufinamide

7.83

6.26-9.4

25.8

20.6-31

Theophylline

9.38

7.5-11.3

18.8

15-22.6

Gabapentin

4.13

3.3-4.96

19.4

15.5-23.3

Pregabalin

1.15

0.92-1.38

8.91

7.13-10.7

Sultiame

1.71

1.37-2.05

11.1

8.88-13.3

Tiagabine (in µg/l)

34.9

27.9-41.9

170

136-204

Topiramate

3.04

2.43-3.65

21.4

17.1-25.7

Vigabatrin

5.35

4.28-6.42

30.7

24.6-36.8

N-Desmethylmesuximide

12.6

10.1-15.1

35.0

28-42

PEMA

2.09

1.67-2.51

8.28

6.62-9.94

Phenytoin

6.00

4.8-7.2

17.4

13.9-20.9

Primidone

5.19

4.15-6.23

14.1

11.3-16.9

Stiripentol

5.57

4.46-6.68

18.2

14.6-21.8

Ethosuximide

33.2

26.6-39.8

81.6

65.3-97.9

Phenobarbital

12.0

9.6-14.4

40.5

32.4-48.6

Valproic acid

43.3

34.6-52

87.7

70.2-105

Zonisamide

8.53

6.82-10.2

36.9

29.5-44.3

Brivaracetam

0.973

0.778-1.17

3.80

3.04-4.56

Perampanel (in µg/l)

175

140-210

1213

970-1456

Retigabine (in µg/l)

243

194-292

1786

1429-2143

Method of Analysis LC-MS/MS
Reconstitution

Carefully remove the rubber stopper from the vials. Add exactly 1.0 ml of distilled water into each vial. Return the stopper and incubate for 10 to 15 minutes at room temperature. Swirl the vials to dissolve the contents until homogeneity.

Storage conditions

Stored below -18 °C and unopened, the lyophilised controls are stable until the expiry date specified on the vial labels. The reconstituted controls can be stored up to 2 weeks light protected and tightly capped at +2 to +8 C. If the controls cannot be used within this period, they should be aliquoted and stored frozen below -18 °C (up to 3 months). For more details about storage conditions please check your instruction manual.

Parameter 10,11-Dihydroxycarbamazepine, 10-OH-Carbamazepine, Brivaracetam, Carbamazepine, Carbamazepine-10,11-epoxide, Ethosuximide, Felbamate, Gabapentin, Lacosamide, Lamotrigine, Levetiracetam (Keppra®), N-Desmethylmesuximide, Oxcarbamazepine, Perampanel, Phenobarbital, Phenylethylmalonamide (PEMA), Pregabalin, Primidone, Retigabine, Rufinamide, Stiripentol, Sultiame, Theophylline, Tiagabine, Topiramate, Valproic Acid, Zonisamide
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